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Author Response: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.作者回复：血清和玻璃体液中HtrA1蛋白水平与10q26位点年龄相关性黄斑变性的遗传风险无关。
Invest Ophthalmol Vis Sci. 2024 Dec 2;65(14):26. doi: 10.1167/iovs.65.14.26.
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Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.血清和玻璃体液中 HtrA1 蛋白水平与 10q26 位点年龄相关性黄斑变性的遗传风险无关。
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Erratum in: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.勘误：血清和玻璃体液中HtrA1蛋白水平与10q26位点年龄相关性黄斑变性的遗传风险无关。
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Letter to the Editor: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.致编辑的信：血清和玻璃体液中HtrA1蛋白水平与10q26位点年龄相关性黄斑变性的遗传风险无关。
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Characterization of the 10q26-orthologue in rhesus monkeys corroborates a functional connection between ARMS2 and HTRA1.恒河猴 10q26 直系同源物的特征分析证实了 ARMS2 和 HTRA1 之间的功能联系。
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Specific correlation between the major chromosome 10q26 haplotype conferring risk for age-related macular degeneration and the expression of .赋予年龄相关性黄斑变性风险的主要染色体10q26单倍型与……的表达之间的特定相关性。 （注：原文中“the expression of”后面缺少具体内容）
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1,25-Dihydroxyvitamin D decreases HTRA1 promoter activity in the rhesus monkey--a plausible explanation for the influence of vitamin D on age-related macular degeneration?1,25-二羟维生素 D 降低食蟹猴 HTRA1 启动子活性——维生素 D 影响年龄相关性黄斑变性的一种合理假说？
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本文引用的文献

1
Letter to the Editor: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.致编辑的信：血清和玻璃体液中HtrA1蛋白水平与10q26位点年龄相关性黄斑变性的遗传风险无关。
Invest Ophthalmol Vis Sci. 2024 Dec 2;65(14):27. doi: 10.1167/iovs.65.14.27.
2
Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.血清和玻璃体液中 HtrA1 蛋白水平与 10q26 位点年龄相关性黄斑变性的遗传风险无关。
Invest Ophthalmol Vis Sci. 2024 Apr 1;65(4):34. doi: 10.1167/iovs.65.4.34.
3
Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro.Gtf2i-β/δ 转录因子与 ARMS2 基因结合会导致 AMD 患者和体外的循环 HTRA1 增加。
J Biol Chem. 2021 Jan-Jun;296:100456. doi: 10.1016/j.jbc.2021.100456. Epub 2021 Feb 24.
4
HTRA1 and TGF-β1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration.新生血管性年龄相关性黄斑变性患者房水中HTRA1和TGF-β1的浓度
Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):162-167. doi: 10.1167/iovs.16-20922.
5
Serum HtrA1 is differentially regulated between early-onset and late-onset preeclampsia.早发型和晚发型子痫前期患者血清HtrA1的表达调控存在差异。
Placenta. 2015 Sep;36(9):990-5. doi: 10.1016/j.placenta.2015.07.001. Epub 2015 Jul 8.

Author Response: Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.

作者信息

Williams Brandi L, Zouache Moussa A, Hageman Gregory S

机构信息

Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States.

出版信息

Invest Ophthalmol Vis Sci. 2024 Dec 2;65(14):26. doi: 10.1167/iovs.65.14.26.

DOI:10.1167/iovs.65.14.26
PMID:39666349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11645747/
Abstract
摘要