Marcus R, Cann C, Madvig P, Minkoff J, Goddard M, Bayer M, Martin M, Gaudiani L, Haskell W, Genant H
Ann Intern Med. 1985 Feb;102(2):158-63. doi: 10.7326/0003-4819-102-2-158.
Bone mass and metabolic features were studied in 17 women distance runners. Eleven of the women had secondary amenorrhea for 1 to 7 years. Six women have maintained regular menses since menarche. Both groups were matched for aerobic capacity, body fat, exercise intensity, and age of menarche. Mineral density of lumbar spine in the amenorrheic runners was lower than that in the cyclic women and age-matched controls, but higher than that in runners with secondary amenorrhea who are less physically active. Mineral density of the radius was normal in both groups. Running-related fractures were more frequent in amenorrheic women. Metabolic assessment showed no differences between groups, except that serum triiodothyronine was lower in the amenorrheic group, perhaps reflecting low calorie intake. Intense exercise may reduce the impact of amenorrhea on bone mass; however, amenorrheic runners remain at high risk for exercise-related fractures.
对17名女性长跑运动员的骨量和代谢特征进行了研究。其中11名女性继发性闭经1至7年。6名女性自初潮起月经一直规律。两组在有氧能力、体脂、运动强度和初潮年龄方面相匹配。闭经长跑运动员的腰椎骨密度低于月经周期正常的女性和年龄匹配的对照组，但高于身体活动较少的继发性闭经跑步者。两组桡骨骨密度均正常。闭经女性与跑步相关的骨折更为常见。代谢评估显示两组之间无差异，只是闭经组血清三碘甲状腺原氨酸较低，这可能反映了热量摄入较低。剧烈运动可能会降低闭经对骨量的影响；然而，闭经的跑步者仍面临与运动相关骨折的高风险。
