高级别胶质瘤头颈部转移的临床及影像学特征：一项单中心病例系列研究
Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series.
作者信息
Eldaya Rami W, Kaya Diana, Williams Michelle, Calle Susana, Schellingerhout Dawid
机构信息
From the Department of Neuroradiology (R.W.E., D.K., S.C.), The University of Texas MD Anderson Cancer Center, Houston, Texas
From the Department of Neuroradiology (R.W.E., D.K., S.C.), The University of Texas MD Anderson Cancer Center, Houston, Texas.
出版信息
AJNR Am J Neuroradiol. 2025 Jan 8;46(1):160-165. doi: 10.3174/ajnr.A8521.
High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.
高级别胶质瘤是最常见的原发性脑肿瘤，但神经外转移极为罕见。部分原因是这些患者的生存期相对较短，以及血脑屏障可能起到的保护作用。鉴于神经外转移罕见，其病理生理学和影像学表现报道不足且了解甚少。在本病例系列中，我们介绍了6例经病理证实的高级别胶质瘤并伴有头颈部神经外转移的患者。我们重点介绍了CT、MRI和PET/CT上转移灶的影像学特征。我们还探讨了高级别胶质瘤转移至头颈部区域的潜在相关性和病理生理学。
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