Louis David N, Wesseling Pieter, Aldape Kenneth, Brat Daniel J, Capper David, Cree Ian A, Eberhart Charles, Figarella-Branger Dominique, Fouladi Maryam, Fuller Gregory N, Giannini Caterina, Haberler Christine, Hawkins Cynthia, Komori Takashi, Kros Johan M, Ng H K, Orr Brent A, Park Sung-Hye, Paulus Werner, Perry Arie, Pietsch Torsten, Reifenberger Guido, Rosenblum Marc, Rous Brian, Sahm Felix, Sarkar Chitra, Solomon David A, Tabori Uri, van den Bent Martin J, von Deimling Andreas, Weller Michael, White Valerie A, Ellison David W
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands.
Brain Pathol. 2020 Jul;30(4):844-856. doi: 10.1111/bpa.12832. Epub 2020 Apr 19.
cIMPACT-NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy) was established to evaluate and make practical recommendations on recent advances in the field of CNS tumor classification, particularly in light of the rapid progress in molecular insights into these neoplasms. For Round 2 of its deliberations, cIMPACT-NOW Working Committee 3 was reconstituted and convened in Utrecht, The Netherlands, for a meeting designed to review putative new CNS tumor types in advance of any future World Health Organization meeting on CNS tumor classification. In preparatory activities for the meeting and at the actual meeting, a list of possible entities was assembled and each type and subtype debated. Working Committee 3 recommended that a substantial number of newly recognized types and subtypes should be considered for inclusion in future CNS tumor classifications. In addition, the group endorsed a number of principles-relating to classification categories, approaches to classification, nomenclature, and grading-that the group hopes will also inform the future classification of CNS neoplasms.
cIMPACT-NOW（中枢神经系统肿瘤分类分子与实践方法信息联盟）的成立是为了评估中枢神经系统肿瘤分类领域的最新进展并提出实用建议，特别是鉴于对这些肿瘤分子认识的快速进展。在其第二轮审议中，cIMPACT-NOW第3工作委员会进行了重组，并在荷兰乌得勒支召开会议，旨在在世卫组织未来任何关于中枢神经系统肿瘤分类的会议之前，对假定的新中枢神经系统肿瘤类型进行审查。在会议的筹备活动以及实际会议期间，收集了一份可能的实体清单，并对每种类型和亚型进行了讨论。第3工作委员会建议，未来的中枢神经系统肿瘤分类应考虑纳入大量新确认的类型和亚型。此外，该小组认可了一些与分类类别、分类方法、命名法和分级相关的原则，希望这些原则也能为未来中枢神经系统肿瘤的分类提供参考。
