Walser H, Mattle H, Keller H M, Janzer R
Arch Neurol. 1985 Jan;42(1):32-8. doi: 10.1001/archneur.1985.04060010038013.
Subcortical and early cortical median nerve somatosensory evoked potentials (SEPs) were examined in 26 patients in hypoxic coma. The amplitude ratio between the negative slope of the scalp response and the following positive trough was determined. The latency difference between the major negative component recorded from the upper neck, N14, and the initial negative potential from the scalp, N20, was also measured. The mean of these parameters in both hemispheres was referred to as mean central conduction time (MCCT) and mean amplitude ratio (MAR). There was a significant difference in MAR in patients with a bilaterally recordable scalp response between those with a good and those with a bad outcome, but no difference in MCCT. Comparison of SEP findings with postmortem examinations suggests that a reduced MAR may yield an estimate of cortical damage in hypoxic coma.
对26例缺氧性昏迷患者进行了皮质下和早期皮质正中神经体感诱发电位（SEP）检查。测定头皮反应负向斜率与随后正向波谷之间的波幅比。还测量了从颈部上段记录的主要负向成分N14与头皮初始负向电位N20之间的潜伏期差异。将两侧半球这些参数的平均值称为平均中枢传导时间（MCCT）和平均波幅比（MAR）。在双侧可记录头皮反应的患者中，预后良好和预后不良者的MAR存在显著差异，但MCCT无差异。SEP检查结果与尸检结果的比较表明，MAR降低可能有助于评估缺氧性昏迷中的皮质损伤。
