Ghosh Abhishek, Kale Akshayee, Laxmi Raj, Naik Shalini S, Subodh B N, Basu Debasish
Department of Psychiatry, Drug Deaddiction and Treatment Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Indian J Psychiatry. 2024 Oct;66(10):956-962. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_432_24. Epub 2024 Oct 17.
Telemedicine-assisted buprenorphine (BNX) induction (TABI) has the potential to reduce the treatment gap for opioid use disorder.
This study investigated the acceptability and feasibility of TABI in India. This was a retrospective study from a specialized addiction treatment center in a teaching hospital.
TABI was introduced in November 2022; patients enrolled till May 2023 were included in the analysis. Feasibility was assessed by the proportion of patients who completed the TABI program, continued treatment for at least 3 months, and self-reported nonprescription opioid use during and after TABI. Acceptability was measured by patient satisfaction with TABI.
Sixty patients were enrolled: Fifty-three patients (88.3%) were retained during the TABI program, and 50 patients (83.3%) remained in treatment at the 3-month follow-up. Thirty-five patients (58.3%) reported using nonprescription opioids during TABI, and 28 patients (46.7%) reported such use after completing the program. Thirty-five (58.3%) were satisfied with the program, and 15 (25%) said they would recommend it to others. Patients who missed scheduled in-person appointments ( < .001) at 1 week, did not return unused BNX-naloxone ( < .001), and were not satisfied ( = .004) were more likely to report nonprescription opioid use. Those who attended the in-person follow-up at 1 week ( = .004) and were satisfied ( = .01) and did not use nonprescription opioids either during ( = .003) or after ( < .001) TABI were more likely to be retained in treatment at 3 months.
The study shows TABI's acceptability and feasibility in a specialized addiction treatment setting; further research is needed for broader applicability.
远程医疗辅助丁丙诺啡(BNX)诱导治疗(TABI)有可能缩小阿片类物质使用障碍的治疗差距。
本研究调查了TABI在印度的可接受性和可行性。这是一项来自教学医院中一家专门成瘾治疗中心的回顾性研究。
TABI于2022年11月引入;纳入分析的患者为截至2023年5月登记的患者。通过完成TABI项目、持续治疗至少3个月以及在TABI期间及之后自我报告非处方阿片类物质使用情况的患者比例来评估可行性。通过患者对TABI的满意度来衡量可接受性。
共纳入60名患者:53名患者(88.3%)在TABI项目期间被保留,50名患者(83.3%)在3个月随访时仍在接受治疗。35名患者(58.3%)报告在TABI期间使用非处方阿片类物质,28名患者(46.7%)报告在完成项目后使用。35名(58.3%)患者对该项目满意,15名(25%)表示会向他人推荐。在1周时错过预定面对面预约的患者(<.001)、未归还未使用的BNX-纳洛酮的患者(<.001)以及不满意的患者(=.004)更有可能报告使用非处方阿片类物质。在1周时参加面对面随访的患者(=.004)、满意的患者(=.01)以及在TABI期间(=.003)或之后(<.001)未使用非处方阿片类物质的患者更有可能在3个月时继续接受治疗。
该研究表明TABI在专门的成瘾治疗环境中具有可接受性和可行性;需要进一步研究以扩大其适用性。