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胫骨近端浅层内侧副韧带附着点及内侧半月板挤出与膝关节骨关节炎的相关性

Correlation of Detachment of Proximal Tibia Superficial Medial Collateral Ligament and Medial Meniscus Extrusion with Knee Osteoarthritis.

作者信息

Jung Woon-Hwa, Wagh Aniket, Seo Minseok, Kunal Kishor

机构信息

Department of Orthopedics, Murup Hospital, Changwon, South Korea.

Department of Orthopaedics, AIIMS, Jodhpur, Rajasthan, India.

出版信息

J Orthop Case Rep. 2024 Dec;14(12):246-251. doi: 10.13107/jocr.2024.v14.i12.5086.

Abstract

INTRODUCTION

The aim of the study is to assess the correlation of detachment of proximal tibia superficial medial collateral ligament (sMCL) and medial meniscus (MM) extrusion with knee osteoarthritis (OA) and its progression.

MATERIALS AND METHODS

This is a prospective study where 165 knees were evaluated using radiographs and magnetic resonance imaging for the severity of OA knee according to Kellgrence-Lawrence grading, MM extrusion, and status of proximal tibia attachment of sMCL. Chi-square test of Independence and Pearson's correlation test were used to assess any correlation among the variables.

RESULTS

The study population had a mean age of 52.93 ± 19.46 years. 106 (64.24%) were males and 59 (35.75 were females. There were 83 (50.30%) left knees and 82 (49.70%) right knees in the study. The percentage of proximal tibia sMCL detachment was more in patients with knee OA than those without OA (85-88.89%). Similarly, the percentage of MM extrusion was maximum in advanced arthritis patients (95%). Both these variables were lowest in non-arthritic group (2.56% and 6.41%, respectively). Statistical analysis showed a significantly positive correlation of detachment of proximal tibial attachment of sMCL as well as MM extrusion with grades of OA of knee (P < 0.001 for both).

CONCLUSION

A detached proximal tibia sMCL and an extruded MM were individually found to have a strong association (Chi-square test) and a positive linear correlation (Pearson's test) with the arthritic condition of the knee. This would suggest a role of both these variables in the progression of knee OA. They can thus be used as prognostic markers for knee OA as well as an important target in the management of knee OA.

摘要

引言

本研究旨在评估胫骨近端浅层内侧副韧带(sMCL)附着点分离及内侧半月板(MM)挤压与膝关节骨关节炎(OA)及其进展之间的相关性。

材料与方法

这是一项前瞻性研究,对165个膝关节进行了X线片和磁共振成像检查,以根据Kellgrence-Lawrence分级评估膝OA的严重程度、MM挤压情况以及sMCL胫骨近端附着点的状态。采用独立性卡方检验和Pearson相关性检验来评估各变量之间的相关性。

结果

研究人群的平均年龄为52.93±19.46岁。男性106例(64.24%),女性59例(35.75%)。研究中左膝83例(50.30%),右膝82例(49.70%)。膝OA患者胫骨近端sMCL附着点分离的百分比高于无OA患者(85%-88.89%)。同样,晚期关节炎患者中MM挤压的百分比最高(95%)。这两个变量在非关节炎组中均最低(分别为2.56%和6.41%)。统计分析显示,sMCL胫骨近端附着点分离以及MM挤压与膝关节OA分级之间存在显著正相关(两者P均<0.001)。

结论

单独发现胫骨近端sMCL附着点分离和MM挤压与膝关节的关节炎状况具有很强的关联(卡方检验)和正线性相关(Pearson检验)。这表明这两个变量在膝OA进展中均起作用。因此,它们可用作膝OA的预后标志物以及膝OA治疗中的重要靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca61/11632477/9618ab815928/JOCR-14-246-g001.jpg

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