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慢性肉芽肿性侵袭性真菌性鼻-鼻窦炎的死亡模式:两例致命病例的见解

Mortality patterns in chronic granulomatous invasive fungal rhinosinusitis: insights from two fatal cases.

作者信息

Aljubran Hussain J, Bamalan Omar A, Alabdulaal Maria R, Almolani Fadhel, Alahmari Mohammad S, Alkhatib Abdulrahman, Almomen Ali

机构信息

College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam 43221, Saudi Arabia.

Department of Surgery, Security Forces Hospital, Dammam 43221, Saudi Arabia.

出版信息

J Surg Case Rep. 2024 Dec 12;2024(12):rjae770. doi: 10.1093/jscr/rjae770. eCollection 2024 Dec.

Abstract

Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a type of invasive fungal rhinosinusitis that is characterized by the presence of pathologic findings of non-caseating granulomas in the paranasal sinuses. This article describes two cases of CGIFRS with fatal outcomes. The first case was for a 36-year-old man who presented with headache, dizziness, and vomiting for 1 month. This patient had received the traditional treatment, although the patient's condition suddenly deteriorated after 1 week of surgery and died due to the disease's complications. Similarly, the second case was for a 31-year-old man who presented with bilateral nasal obstruction and left eye proptosis for 1 year. This patient had a recurrence of CGIFRS after the first presentation, which was complicated by a cerebral abscess after 2 months of surgery. This study, therefore, underscores the severity of CGIFRS as a potentially fatal disease.

摘要

慢性肉芽肿性侵袭性真菌性鼻-鼻窦炎(CGIFRS)是侵袭性真菌性鼻-鼻窦炎的一种类型,其特征是鼻窦中存在非干酪样肉芽肿的病理表现。本文描述了两例CGIFRS导致死亡的病例。第一例是一名36岁男性,出现头痛、头晕和呕吐1个月。该患者接受了传统治疗,尽管患者在手术后1周病情突然恶化,最终因疾病并发症死亡。同样,第二例是一名31岁男性,出现双侧鼻塞和左眼突出1年。该患者首次发病后CGIFRS复发,术后2个月并发脑脓肿。因此,本研究强调了CGIFRS作为一种潜在致命疾病的严重性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be6c/11635823/2570dd5568c2/rjae770f1.jpg

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