Popalzai Muhammad J, Kushawaha Anurag, Mobarakai Neville, Asrar Rohail, Durrani Farida
Department of Medicine, Staten Island University Hospital, Division of Infectious Diseases 475 Seaview Avenue, Staten Island, NY 10305, USA.
Cases J. 2009 Dec 31;2:9406. doi: 10.1186/1757-1626-2-9406.
Cerebral angioinvasion is a fatal complication of disseminated aspergillosis and has been rarely described in diabetic population in the absence of ketoacidosis. We present a case of invasive fungal sinusitis in a 79 year old diabetic man who presented with chronic frontal headaches. Despite appropriate medical and surgical treatment, the disease progressed and the patient eventually succumbed to a fatal ruptured mycotic aneurysm. We emphasize that clinicians should consider this in the differential diagnoses of all diabetics who present with chronic sinusitis, as early diagnosis could be the key in the successful treatment.
脑血管侵袭是播散性曲霉病的一种致命并发症，在非酮症酸中毒的糖尿病患者中鲜有报道。我们报告一例79岁患慢性额部头痛的糖尿病男性侵袭性真菌性鼻窦炎病例。尽管给予了适当的药物和手术治疗，病情仍进展，患者最终死于致命的霉菌性动脉瘤破裂。我们强调，临床医生在所有患慢性鼻窦炎的糖尿病患者的鉴别诊断中都应考虑到这一点，因为早期诊断可能是成功治疗的关键。
