De Vos Marie, Meyns Bart, Quarck Rozenn Anne, Belge Catharina, Godinas Laurent, Rex Steffen, Vlasselaers Dirk, Delcroix Marion, Verbelen Tom
Department of Cardiac Surgery, University Hospitals Leuven, Leuven, Belgium.
Clinical Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
JTCVS Tech. 2024 Oct 18;28:65-72. doi: 10.1016/j.xjtc.2024.09.021. eCollection 2024 Dec.
We aimed to explore the feasibility of an inverted-T upper hemisternotomy approach for pulmonary endarterectomy (PEA) and report the results after 17 cases.
PEA was conducted through a 7-cm skin incision using an inverted-T upper hemisternotomy across the third intercostal spaces. Cardiopulmonary bypass (CPB) was established through central arterial and percutaneous femoral dual-staged venous cannulation. Perioperative and hemodynamic data were compared with 17 previous conventional PEAs performed by the same surgeon.
From July 2022 to September 2023, 22 PEAs were performed, 17 through inverted-T upper hemisternotomy. Contraindications were an inferior caval vein filter, concomitant coronary revascularization or mitral valve surgery, pulmonary artery intimal sarcoma, and an emergency. Compared with 17 preceding conventional PEAs, there was no significant difference in demographics or in CPB time (274 [256-301] vs 264 [250-274] minutes, = .1629), deep hypothermic circulatory arrest time (56 [45-65] vs 54 [50-58] minutes, = .9587), preoperative pulmonary vascular resistance (4.12 [3.10-4.79] vs 4.49 [3.25-6.24] Wood units, = .5890), 6-month postoperative pulmonary vascular resistance (1.90 [1.40-2.56] vs 1.83 [1.44-2.20] Wood units, = .6374), or hospital stay (10 [8-12] vs 11 [9-14] days, = .3327). Intravenous opioid use (0.29 [0.21-0.83] vs 2.99 [1.31-4.33] mg, < 1.10) was significantly lower.
PEA using an inverted-T upper hemisternotomy approach is feasible and safe and obtains similar hemodynamic results compared with a full sternotomy approach without prolonging CPB and deep hypothermic circulatory arrest times. It offers bilateral treatment via a single incision and has few contraindications.
我们旨在探讨倒T形上半胸骨切开术用于肺动脉内膜剥脱术(PEA)的可行性,并报告17例患者的手术结果。
采用倒T形上半胸骨切开术,经第三肋间7cm皮肤切口进行PEA。通过中心动脉和经皮股静脉双阶段插管建立体外循环(CPB)。将围手术期和血流动力学数据与同一位外科医生之前进行的17例传统PEA进行比较。
2022年7月至2023年9月,共进行了22例PEA,其中17例采用倒T形上半胸骨切开术。禁忌证包括下腔静脉滤器、同期冠状动脉血运重建或二尖瓣手术、肺动脉内膜肉瘤以及急诊情况。与之前的17例传统PEA相比,在人口统计学数据或CPB时间(274[256 - 301]分钟 vs 264[250 - 274]分钟,P = 0.1629)、深低温循环停搏时间(56[45 - 65]分钟 vs 54[50 - 58]分钟,P = 0.9587)、术前肺血管阻力(4.12[3.10 - 4.79] vs 4.49[3.25 - 6.24]伍德单位,P = 0.5890)、术后6个月肺血管阻力(1.90[1.40 - 2.56] vs 1.83[1.44 - 2.20]伍德单位,P = 0.6374)或住院时间(10[8 - 12]天 vs 11[9 - 14]天,P = 0.3327)方面均无显著差异。静脉使用阿片类药物的量(0.29[0.21 - 0.83] vs 2.99[1.31 - 4.33]mg,P < 0.001)显著更低。
采用倒T形上半胸骨切开术进行PEA是可行且安全的,与全胸骨切开术相比,在不延长CPB和深低温循环停搏时间的情况下可获得相似的血流动力学结果。它通过单一切口提供双侧治疗,且禁忌证较少。