Guth Stefan, Mayer Eckhard, Prüfer Diethard, Wiedenroth Christoph B
Department of Thoracic Surgery, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Ann Cardiothorac Surg. 2022 Mar;11(2):180-188. doi: 10.21037/acs-2021-pte-185.
Chronic thromboembolic pulmonary hypertension (CTEPH) remains a rare and underdiagnosed disease. After one or several episodes of acute pulmonary embolism, around 3% of patients develop CTEPH and two-thirds of these patients are potential surgical candidates. Besides surgery, additional treatment modalities are pulmonary arterial hypertension medication and balloon pulmonary angioplasty. Patients should be evaluated in CTEPH expert centers to ensure the most appropriate therapy. Pulmonary endarterectomy (PEA) is a complex, but standardized surgical procedure aiming to clear the obstructed pulmonary arteries completely. For optimal visualization, deep hypothermic circulatory arrest is a prerequisite. This article will give an overview of the evaluation, indication and surgical management of patients with CTEPH.
慢性血栓栓塞性肺动脉高压(CTEPH)仍然是一种罕见且诊断不足的疾病。在一次或几次急性肺栓塞发作后,约3%的患者会发展为CTEPH,其中三分之二的患者是潜在的手术候选者。除了手术,其他治疗方式包括肺动脉高压药物治疗和球囊肺动脉血管成形术。患者应在CTEPH专家中心接受评估,以确保采用最合适的治疗方法。肺动脉内膜剥脱术(PEA)是一种复杂但标准化的外科手术,旨在完全清除阻塞的肺动脉。为了实现最佳可视化,深度低温循环停止是一个先决条件。本文将概述CTEPH患者的评估、适应症和手术管理。