Boshra Hani
Faculty of Veterinary Medicine, Department of Pathology, Fundamental and Applied Research for Animals and Health (FARAH), University of Liège, Liège, Belgium.
Methods Mol Biol. 2025;2893:1-10. doi: 10.1007/978-1-0716-4338-9_1.
The bunyaviruses are an ever-expanding group of RNA viruses that have been linked to a variety of different diseases around the world. First characterized nearly a century ago, over 500 different types of bunyaviruses have been characterized thus far, with hosts ranging from mammals to plants to single-celled organisms. As many of the currently described bunyaviruses have been found to be vector-borne, with transmission being mediated by either insects or rodents, these viruses have incorporated immune-evasive molecules into their relatively small genome. As these viruses have been implicated in a number of public health threats, there is an increased interest in performing experiments that could improve our understanding of these infectious agents. Therefore, the objectives of this book are outlined in this chapter, with a variety of techniques being described for the study of a variety of different bunyaviruses.
布尼亚病毒是一类不断扩大的RNA病毒，与世界各地的多种不同疾病有关。近一个世纪前首次被鉴定，迄今为止已鉴定出500多种不同类型的布尼亚病毒，其宿主范围从哺乳动物到植物再到单细胞生物。由于目前描述的许多布尼亚病毒已被发现是媒介传播的，传播由昆虫或啮齿动物介导，这些病毒已将免疫逃避分子纳入其相对较小的基因组中。由于这些病毒与许多公共卫生威胁有关，人们对进行能够增进我们对这些传染源理解的实验的兴趣日益增加。因此，本章概述了本书的目标，并描述了用于研究多种不同布尼亚病毒的各种技术。
