澳大利亚的布鲁里溃疡：新南威尔士州贝特曼斯湾出现新的地方病疫源地的证据。
Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
作者信息
Hossain Mehrab E, Keighley Caitlin, Buultjens Andrew H, Porter Jessica L, Johnson Paul D R, Stinear Timothy P, Globan Maria, Lavender Caroline J, Lacey Jake A, Sherry Norelle L, Forsyth Anton, Formby Mark, Marr Ian
机构信息
Department of Infectious Diseases and Microbiology, The Canberra Hospital, Australian Capital Territory, Australia.
Southern.IML Pathology, Sonic Healthcare, Wollongong, New South Wales, Australia.
出版信息
PLoS Negl Trop Dis. 2024 Dec 13;18(12):e0012702. doi: 10.1371/journal.pntd.0012702. eCollection 2024 Dec.
We describe two locally acquired cases of Mycobacterium ulcerans infection (Buruli ulcer) in the town of Batemans Bay on the east coast of New South Wales (NSW), Australia, 150 km north of Eden, the only other place in NSW where Buruli ulcer has likely been locally acquired. Genomic analysis showed that the bacterial isolates from the cases were identical but belonged to a phylogenetically distinct M. ulcerans clade that was most closely related to the isolate from the earlier case in Eden to the south. It is proposed that Batemans Bay is a new endemic focus of human Buruli ulcer transmission.
我们描述了澳大利亚新南威尔士州（NSW）东海岸贝特曼斯湾镇两例本地感染溃疡分枝杆菌（布鲁里溃疡）的病例，该镇位于伊登以北150公里处，伊登是新南威尔士州另一个可能存在本地感染布鲁里溃疡的地方。基因组分析表明，这两例病例的细菌分离株相同，但属于一个系统发育上不同的溃疡分枝杆菌分支，与南部伊登早期病例的分离株关系最为密切。据推测，贝特曼斯湾是人类布鲁里溃疡传播的一个新的地方病疫源地。
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