Rey J A, Bello J, de Campos J M, Benítez J, Valcárcel E, Castro P M
Cancer Genet Cytogenet. 1985 Feb 1;15(1-2):129-36. doi: 10.1016/0165-4608(85)90140-2.
C-banding studies were performed on cultured peripheral blood lymphocytes from 100 patients with tumors of the nervous system and 30 controls. The classification of Patil and Lubs and the heterochromatic index (HI) of Neeley were used to evaluate the heteromorphism. No overall significant differences were found in the frequency of C-band variants when the findings in both tumoral populations and controls were compared, but we did find an excess of 9qh inversions in some groups of tumor patients. An increase in the amount of heterochromatin in patients with pituitary adenomas and high malignancy grade astrocytomas was noted.
对100例神经系统肿瘤患者和30例对照者的培养外周血淋巴细胞进行了C带研究。采用帕蒂尔和卢布斯的分类方法以及尼利的异染色质指数（HI）来评估异态性。比较肿瘤患者群体和对照者的研究结果时，未发现C带变异频率存在总体显著差异，但我们确实在某些肿瘤患者组中发现9qh倒位过多。垂体腺瘤患者和高恶性度星形细胞瘤患者的异染色质数量增加。
