Okumura Kohki, Tamura Takahiko, Funakoshi Yusuke, Teranishi Hiroo
Tokyo Chuo Beauty Clinic, K's Square Building 3F, 2-8-15 Sonezaki, Kita-ku, Osaka-shi, Osaka-fu, UmedaOsaka, Japan.
Medical Frontier Inc., Tokyo, Japan.
Aesthetic Plast Surg. 2025 Jun;49(11):2880-2886. doi: 10.1007/s00266-024-04615-9. Epub 2024 Dec 13.
The incidence rate of submental liposuction has been increasing in recent years. Although this procedure is relatively simple, serious complications, including fatalities, have been reported, primarily owing to intraoperative and postoperative bleeding.
To enhance the safety of liposuction, we examined the efficacy of Beriplast® P (CSL Behring, Melbourne, Australia), a physiological tissue adhesive fibrin sealant, in reducing postoperative swelling. Swelling was measured using the image analysis software VECTRA® (Vectra AI, Inc., CA, USA). Twenty-nine cases of submental liposuction performed from February to August 2024 were analyzed for tissue volume changes immediately postoperatively and at the time of suture removal, comparing those who received the fibrin sealant to those who did not.
The group using the fibrin sealant had significantly less postoperative swelling compared to the group that did not use the fibrin sealant (p<0.001).
The fibrin sealant may be used to effectively suppress postoperative swelling, reducing the risk of complications and improving patient satisfaction, thereby enhancing the overall safety and effectiveness of cosmetic surgery.
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近年来，颏下吸脂术的发生率一直在上升。尽管该手术相对简单，但已报道了包括死亡在内的严重并发症，主要是由于术中及术后出血。
为提高吸脂术的安全性，我们研究了生理性组织粘合剂纤维蛋白密封剂百因止（Beriplast® P，澳大利亚墨尔本CSL Behring公司）在减轻术后肿胀方面的疗效。使用图像分析软件VECTRA®（美国加利福尼亚州Vectra AI公司）测量肿胀情况。分析了2024年2月至8月进行的29例颏下吸脂术病例术后即刻及拆线时的组织体积变化，比较了使用纤维蛋白密封剂的患者和未使用的患者。
与未使用纤维蛋白密封剂的组相比，使用该密封剂的组术后肿胀明显减轻（p<0.001）。
纤维蛋白密封剂可有效抑制术后肿胀，降低并发症风险，提高患者满意度，从而提高整形手术的整体安全性和有效性。
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