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一名免疫功能低下旅行者的迁延性片山综合征:评估治愈情况的挑战

Protracted Katayama syndrome in an immunocompromised traveller: the challenge of assessing cure.

作者信息

Van Den Broucke Steven, Schrijvers Rik, Van Esbroeck Marjan, Coppens Jasmine, Van Lieshout Lisette, Bottieau Emmanuel

机构信息

Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.

Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.

出版信息

J Travel Med. 2025 Mar 11;32(2). doi: 10.1093/jtm/taae149.

Abstract

We describe a case of prolonged Katayama syndrome in an immunocompromised traveller. We highlight the difficulty of evaluating a cure due to persistent polymerase chain reaction (PCR) positivity and fluctuating markers. We discuss limitations of current diagnostic assays and advocate for improved access to reliable markers like the circulating anodic antigen test.

摘要

我们描述了一例免疫功能低下旅行者发生的迁延性急性期综合征。我们强调了由于聚合酶链反应(PCR)持续阳性和指标波动而评估治愈情况的困难。我们讨论了当前诊断检测方法的局限性,并主张增加获得可靠指标(如循环阳极抗原检测)的途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/564f/11896843/4670859bb731/taae149f1.jpg

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