Bessar Hagar, Nassar Amany, Saad Eldin Rehab M, Anis Nourhan
Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Arch Dermatol Res. 2024 Dec 14;317(1):123. doi: 10.1007/s00403-024-03420-3.
With aging, facial lines on the forehead and glabella are sometimes converted from dynamic to static giving an aged appearance. Polydioxanone sutures are popular now as a management option in correcting deep static wrinkles on the upper face .This work was conducted to assess the synergistic efficacy of combining Botulinum toxin injection with Polydioxanone threads on the upper face static wrinkles. 30 adult patients with static wrinkles on forehead were included in this work. They were randomly distributed to one of two groups; threads insertion either alone or with Botulinum toxin injection. Treatment efficacy was evaluated after 2 months by using a Global Aesthetic Improvement Scale. Our results displayed a statistically significant improvement in forehead wrinkles in group II compared to group I (P=0.001). There was a trend toward improvement that did not reach significance in glabellar wrinkles in group II compared to group I, but this improvement did not reach the statistical significant level (P<0.112). Absorbable polydioxanone threads can be considered as a third line procedure for wrinkle correction beyond Botulinum toxin and soft tissue fillers. Threads alone don't fit all situations but their combination with Botulinum toxin can give a better natural-looking appearance with more patient satisfaction.
随着年龄增长，前额和眉间的面部皱纹有时会从动态纹转变为静态纹，从而呈现出衰老的外观。聚二氧六环酮缝线作为一种治疗上半脸深层静态皱纹的方法，目前很受欢迎。本研究旨在评估肉毒杆菌毒素注射与聚二氧六环酮线联合应用对上半脸静态皱纹的协同疗效。本研究纳入了30例前额有静态皱纹的成年患者。他们被随机分为两组之一；单独进行线植入或联合肉毒杆菌毒素注射。2个月后使用全球美学改善量表评估治疗效果。我们的结果显示，与第一组相比，第二组前额皱纹有统计学意义上的显著改善（P=0.001）。与第一组相比，第二组眉间皱纹有改善趋势，但未达到显著水平，且这种改善未达到统计学显著水平（P<0.112）。可吸收的聚二氧六环酮线可被视为除肉毒杆菌毒素和软组织填充剂之外的第三种皱纹矫正方法。单独使用线并不适用于所有情况，但它们与肉毒杆菌毒素联合使用可以使外观更自然，患者满意度更高。
