硬化疗法治疗遗传性出血性毛细血管扩张症：病例系列
Treatment of hereditary hemorrhagic telangiectasias with sclerotherapy: A case series.
作者信息
Ji Jenny, Peterson Andrew M, Piccirillo Jay F
机构信息
Department of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA.
Department of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA; Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA.
出版信息
Am J Otolaryngol. 2025 Jan-Feb;46(1):104537. doi: 10.1016/j.amjoto.2024.104537. Epub 2024 Dec 5.
BACKGROUND
Hereditary hemorrhagic telangiectasia (HHT) is characterized by abnormal blood vessel formation. One treatment for HHT-related arteriovenous malformations (AVMs) is sclerotherapy, which collapses the blood vessels by irritating the endothelial lining.
METHODS
This case series describes two HHT patients undergoing in-office sodium tetradecyl sulfate sclerotherapy for non-nasal telangiectasias and AVMs. The first patient had AVMs on the red lip while the second patient had an AVM and several telangiectasias on the tongue.
RESULTS
Both patients' AVMs required only one treatment visit and were no longer noticeable within a week. Neither of the patients had any side effects from treatment.
CONCLUSION
Sclerotherapy was used to successfully treat HHT-related AVMs in-office with no scarring and is an option that should be considered by providers.
背景
遗传性出血性毛细血管扩张症（HHT）的特征是血管形成异常。治疗HHT相关动静脉畸形（AVM）的一种方法是硬化疗法，即通过刺激内皮细胞衬里使血管塌陷。
方法
本病例系列描述了两名接受十四烷基硫酸钠硬化疗法治疗非鼻毛细血管扩张症和AVM的HHT患者。第一名患者的红唇上有AVM，而第二名患者的舌头上有一个AVM和几个毛细血管扩张症。
结果
两名患者的AVM仅需一次治疗就诊，一周内就不再明显。两名患者均未出现治疗副作用。
结论
硬化疗法成功地在门诊治疗了HHT相关的AVM，且无瘢痕形成，是医疗服务提供者应考虑的一种选择。
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