在合适的时机：将精准治疗应用于新诊断的癌症。

At the right time: Moving precision therapy to newly diagnosed cancer.

作者信息

Wahida Adam, George Ben, Kurzrock Razelle

机构信息

Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.

MCW Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.

出版信息

Med. 2024 Dec 13;5(12):1463-1465. doi: 10.1016/j.medj.2024.10.017.

DOI:10.1016/j.medj.2024.10.017

PMID:39674173

Abstract

Precision oncology aims to match the right drug(s) to the right patient. Equally important is ensuring that precision therapies are offered at the right time. Transformative, rather than incremental, outcome improvement may require treatment at diagnosis rather than in the advanced/metastatic setting after genomic evolution.

摘要

精准肿瘤学旨在为合适的患者匹配合适的药物。同样重要的是要确保在正确的时间提供精准治疗。实现变革性而非渐进性的结果改善可能需要在诊断时而非在基因组进化后的晚期/转移性阶段进行治疗。