Leff D R, Leff A R
Chest. 1985 Feb;87(2):206-11.
Twenty-eight metropolitan health departments in the United States reporting more than 200 cases annually were surveyed to determine the standard of practice in the control of pulmonary tuberculosis. The results were compared to previous surveys done in 1978 and 1980 to determine the impact of policy changes recommended by the American Thoracic Society, American College of Chest Physicians, and Centers for Disease Control and recent reports of innovative chemotherapeutic methods. A high degree of uniformity in chemoprophylaxis practices again was demonstrated. In contrast to our previous survey of 1980, most programs now use rifampin-containing regimens with short (less than 12 month) course chemotherapy as the primary initial treatment regimen for tuberculosis. Mean duration of treatment for tuberculosis decreased from 20.2 +/- 2.1 months in 1980 to 11.7 +/- 1.0 months in 1984. Intermittent chemotherapeutic regimens also were used more frequently in 1984. However, substantial variance from other recommended guidelines still is prevalent among the major metropolitan programs in the United States.
对美国每年报告超过200例病例的28个大城市卫生部门进行了调查，以确定控制肺结核的实践标准。将结果与1978年和1980年进行的先前调查进行比较，以确定美国胸科学会、美国胸科医师学会和疾病控制中心推荐的政策变化以及近期创新化疗方法报告的影响。化学预防实践再次显示出高度的一致性。与我们1980年的先前调查相比，现在大多数项目使用含利福平的方案和短程（少于12个月）化疗作为结核病的主要初始治疗方案。结核病的平均治疗时间从1980年的20.2±2.1个月降至1984年的11.7±1.0个月。1984年也更频繁地使用间歇化疗方案。然而，在美国主要大城市项目中，与其他推荐指南仍存在很大差异。
