Rojek Amanda, Fieggen Joshua, Paterson Amy, Byakika-Kibwika Pauline, Camara Modet, Comer Kim, Fletcher Tom E, Günther Stephan, Jonckheere Sylvie, Mwima Gerald, Dunning Jake, Horby Peter
Pandemic Sciences Institute, Oxford, UK.
Pandemic Sciences Institute, Oxford, UK.
Lancet Infect Dis. 2025 Mar;25(3):e177-e188. doi: 10.1016/S1473-3099(24)00727-8. Epub 2024 Dec 12.
A key lesson from the west Africa (2014-16) Ebola disease epidemic was that outbreak responses fail when they respond to patients through a narrow clinical lens without considering the broader community and social context of care. Here, in the second of two Series papers on the modern landscape of Ebola disease, we review progress made in the last decade to improve patient-centred care. Although the biosafety imperatives of treating Ebola disease remain, recent advances show how to mitigate these so that patients are cared for in a safe and dignified manner that encourages early treatment-seeking behaviour and provides support after the return of patients to their communities. We review advances in diagnostics, including faster Ebola disease detection via real-time RT-PCR, and consider design improvements in Ebola disease treatment units that enhance patient safety and dignity. We also review advances in care provision, such as the integration of palliative care and mobile communication into routine care, and address how greater access to research is possible through harmonised clinical trials. Finally, we discuss how strengthened community engagement and psychosocial programmes are addressing stigma and providing holistic support for survivors.
西非(2014 - 16年)埃博拉疫情带来的一个关键教训是,如果在应对患者时仅从狭隘的临床角度出发,而不考虑更广泛的社区和社会护理背景,疫情应对就会失败。在此,在关于埃博拉疾病现代格局的两篇系列论文的第二篇中,我们回顾了过去十年在改善以患者为中心的护理方面取得的进展。尽管治疗埃博拉疾病的生物安全要求依然存在,但最近的进展表明如何减轻这些要求,以便以安全且有尊严的方式护理患者,这种方式鼓励患者尽早寻求治疗,并在患者返回社区后提供支持。我们回顾了诊断方面的进展,包括通过实时逆转录聚合酶链反应更快地检测埃博拉疾病,并考虑了埃博拉疾病治疗单元在设计上的改进,这些改进提高了患者的安全性和尊严。我们还回顾了护理提供方面的进展,例如将姑息治疗和移动通信纳入常规护理,并探讨如何通过协调临床试验让更多人参与研究。最后,我们讨论了加强社区参与和心理社会项目如何消除污名化,并为幸存者提供全面支持。