Sun Ming-Zhu, Wang Xin, Li Ying-Chen, Liu Yu-Hang, Yu Yi, Ren Liu-Jie, Gu Wei, Yao Wei
Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Department of Aeronautics and Astronautics, Fudan University, Shanghai 200433, China.
Department of Traditional Chinese Medicine, Naval Medical University, Shanghai 200433, China.
J Integr Med. 2025 Jan;23(1):66-78. doi: 10.1016/j.joim.2024.11.007. Epub 2024 Dec 3.
The analgesic effect of acupuncture has been widely accepted. Nevertheless, the mechanism behind its analgesic effect remains elusive, thus impeding the progress of research geared toward enhancing the analgesic effect of acupuncture. This paper investigated the role of acupuncture needle surface textures on acupuncture's analgesic effect by creating four experimental acupuncture needles with different patterns of surface augmentation.
Four types of acupuncture needles with different surface textures (the lined needle, circle needle, sandpaper needle, and threaded needle) were designed. Additionally, the force/torque measurement system used a robot arm and mechanical sensor to measure the force on the needle during insertion and manipulation. To perform acupuncture analgesia experiments, four experimental acupuncture needles and a normal needle were inserted into the Zusanli (ST36) acupoint of rats with inflammatory pain. By comparing the force and torque and the analgesic efficacy of the different acupuncture needles, these experiments tested the role of acupuncture needle body texture on acupuncture analgesia.
The analgesic effects of different acupuncture needle body textures varied. Specifically, the force required to penetrate the skin with the lined needle was not greater than that for the normal needle; however, the needle with inscribed circles and the sandpaper-roughened needle both required greater force for insertion. Additionally, the torque of the lined needle reached 2 × 10 N·m under twisting manipulation, which was four times greater the torque of a normal needle (5 × 10 N·m). Furthermore, the lined needle improved pain threshold and mast cell degranulation rate compared to the normal needle.
Optimizing the texture of acupuncture needles can enhance acupuncture analgesia. The texture of our experimental acupuncture needles had a significant impact on the force needed to penetrate the skin and the torque needed to manipulate the needle; it was also linked to variable analgesic effects. This study provides a theoretical basis for enhancing the analgesic efficacy of acupuncture through the modification of needles and promoting the development of acupuncture therapy. Please cite this article as: Sun MZ, Wang X, Li YC, Liu YH, Yu Y, Ren LJ, Gu W, Yao W. Effects of acupuncture needle modification on acupuncture analgesia. J Integr Med. 2025; 23(1): 66-78.
针刺的镇痛作用已被广泛认可。然而,其镇痛作用背后的机制仍不明确,这阻碍了旨在增强针刺镇痛效果的研究进展。本文通过制作四种具有不同表面增强图案的实验用针灸针,研究了针灸针表面纹理对针刺镇痛效果的作用。
设计了四种具有不同表面纹理的针灸针(线条针、圆圈针、砂纸针和螺纹针)。此外,力/扭矩测量系统使用机械臂和机械传感器来测量进针和操作过程中针上的力。为了进行针刺镇痛实验,将四种实验用针灸针和一根普通针插入患有炎性疼痛的大鼠足三里(ST36)穴位。通过比较不同针灸针的力、扭矩和镇痛效果,这些实验测试了针灸针身纹理对针刺镇痛的作用。
不同针灸针身纹理的镇痛效果各不相同。具体而言,使用线条针穿透皮肤所需的力不大于普通针;然而,刻有圆圈的针和砂纸粗糙化的针插入时都需要更大的力。此外,在扭转操作下,线条针的扭矩达到2×10 N·m,是普通针扭矩(5×10 N·m)的四倍。此外,与普通针相比,线条针提高了痛阈和肥大细胞脱颗粒率。
优化针灸针的纹理可以增强针刺镇痛效果。我们实验用针灸针的纹理对穿透皮肤所需的力和操作针所需的扭矩有显著影响;它还与不同的镇痛效果有关。本研究为通过改进针具提高针刺镇痛疗效及推动针刺疗法发展提供了理论依据。请引用本文:孙MZ,王X,李YC,刘YH,于Y,任LJ,顾W,姚W。针灸针改良对针刺镇痛的影响。《整合医学杂志》。2025;23(1): 66 - 78。