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Detection and Characterisation of Wasp Venom-Specific T Cells Using the ARTE Method in Allergic Patients.

作者信息

Kraft Magdalena, Saleh Samira, Heine Guido, Scheffold Alexander, Bacher Petra, Worm Margitta

机构信息

Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

出版信息

Clin Exp Allergy. 2025 May;55(5):427-429. doi: 10.1111/cea.14606. Epub 2024 Dec 15.

DOI:10.1111/cea.14606
PMID:39675967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12088834/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f64/12088834/ad88c0c846b1/CEA-55-427-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f64/12088834/ad88c0c846b1/CEA-55-427-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f64/12088834/ad88c0c846b1/CEA-55-427-g001.jpg

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本文引用的文献

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Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans.特异性效应性 Th2 细胞对变应原的识别使人类的调节性 T 细胞反应能够依赖于 IL-2 的激活。
Allergy. 2023 Mar;78(3):697-713. doi: 10.1111/all.15512. Epub 2022 Sep 20.
2
Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector T2 subsets.单细胞分析花生过敏患者的花生反应性 T 细胞揭示了异质性效应 T2 亚群。
J Allergy Clin Immunol. 2018 Jun;141(6):2107-2120. doi: 10.1016/j.jaci.2017.11.060. Epub 2018 Jan 31.
3
A phenotypically and functionally distinct human T2 cell subpopulation is associated with allergic disorders.
一种表型和功能上不同的人类T2细胞亚群与过敏性疾病有关。
Sci Transl Med. 2017 Aug 2;9(401). doi: 10.1126/scitranslmed.aam9171.
4
Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans.调节性 T 细胞特异性指导人类对气传变应原的耐受与过敏。
Cell. 2016 Nov 3;167(4):1067-1078.e16. doi: 10.1016/j.cell.2016.09.050. Epub 2016 Oct 20.
5
Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals.蜜蜂和黄蜂毒液过敏个体中升高且交叉反应的CD1a反应性T细胞。
Eur J Immunol. 2016 Jan;46(1):242-52. doi: 10.1002/eji.201545869. Epub 2015 Nov 17.
6
Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire.抗原反应性 T 细胞的富集用于直接、高分辨率分析人类幼稚和记忆 Th 细胞库。
J Immunol. 2013 Apr 15;190(8):3967-76. doi: 10.4049/jimmunol.1202221. Epub 2013 Mar 11.
7
Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects.昆虫毒液免疫疗法可诱导白细胞介素-10的产生以及Th2向Th1的转变，并改变毒液过敏受试者的表面标志物表达。
Eur J Immunol. 1997 May;27(5):1131-9. doi: 10.1002/eji.1830270513.
8
Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: comparison of rush and conventional immunotherapy.蜂毒免疫疗法可诱导细胞因子反应从以TH-2为主转变为以TH-1为主的模式：快速免疫疗法与传统免疫疗法的比较。
Clin Exp Allergy. 1995 Sep;25(9):828-38. doi: 10.1111/j.1365-2222.1995.tb00025.x.
9
Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures.蜂毒免疫疗法可使特异性变应原刺激的T细胞培养物中白细胞介素-4和白细胞介素-5水平降低，干扰素-γ分泌增加。
J Immunol. 1995 Apr 15;154(8):4187-94.