Rao Karan, Baer Alexandra, Bapat Vinayak N, Piazza Nicolo, Hansen Peter, Prendergast Bernard, Bhindi Ravinay
Royal North Shore Hospital, Sydney, Australia.
University of Sydney, Sydney, Australia.
EuroIntervention. 2024 Dec 16;20(24):e1493-e1504. doi: 10.4244/EIJ-D-24-00332.
Transcatheter aortic valve implantation (TAVI) is a safe and effective procedure for the treatment of aortic stenosis. With the recently broadened indications, there is a larger cohort of patients likely to outlive their first transcatheter heart valve (THV). This review discusses relevant lifetime planning considerations, focusing on the utility of preprocedural computed tomography imaging to help implanters future-proof their patients who are likely to outlive their first valve. The initial priority is to optimise the index procedure by maximising THV haemodynamic function and durability. This involves maximising the effective orifice area, minimising the risk of new pacemaker implantation, reducing paravalvular regurgitation, and preventing coronary obstruction and annular rupture. In patients requiring a second valve procedure, a significant proportion will require a TAVI-in-TAVI, and implanters should consider the key priorities for a redo procedure, including the increased risks of patient-prosthesis mismatch and conduction abnormalities, promoting coronary reaccessibility, and preventing coronary obstruction and sinus sequestration. Careful planning can identify potential hurdles as well as predict the feasibility and likely outcomes of redo-TAVI, to help individualise care over the lifetime of each patient.
经导管主动脉瓣植入术(TAVI)是治疗主动脉瓣狭窄的一种安全有效的方法。随着适应症最近的扩大,有更多患者可能在其首个经导管心脏瓣膜(THV)植入后存活更长时间。本综述讨论了相关的终身规划考量因素,重点关注术前计算机断层扫描成像的作用,以帮助植入者为可能在首个瓣膜植入后存活更长时间的患者做好未来的准备。首要任务是通过最大化THV的血流动力学功能和耐久性来优化首次手术。这包括最大化有效瓣口面积、最小化新植入起搏器的风险、减少瓣周反流、预防冠状动脉阻塞和瓣环破裂。在需要进行二次瓣膜手术的患者中,很大一部分将需要进行TAVI-in-TAVI,植入者应考虑再次手术的关键优先事项,包括患者-假体不匹配和传导异常风险增加、促进冠状动脉可及性以及预防冠状动脉阻塞和窦隔离。精心规划可以识别潜在障碍,并预测再次TAVI的可行性和可能结果,以帮助为每位患者的一生提供个性化护理。