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硬斑病的一种不寻常表现：病例报告

An Unusual Presentation of Morphea: A Case Report.

作者信息

Al Badi Asiya, Al-Khamisani Maryam

机构信息

General Practice, Directorate of Primary Health Care, Al Buraimi, OMN.

Dermatology, Al Buraimi Hospital, Al Buraimi, OMN.

出版信息

Cureus. 2024 Nov 13;16(11):e73614. doi: 10.7759/cureus.73614. eCollection 2024 Nov.

DOI:10.7759/cureus.73614
PMID:39677209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11642178/
Abstract

Morphea is a chronic inflammatory skin disease characterized by skin fibrosis with variable clinical presentation. We report a case of a young woman who presented with asymptomatic progressive indurated short cords on the neck. A diagnosis of morphea was made based on clinical and histopathological findings. She had clinical improvement after starting topical corticosteroids alternating with topical tacrolimus.

摘要

硬斑病是一种慢性炎症性皮肤病，其特征为皮肤纤维化，临床表现多样。我们报告一例年轻女性病例，该患者颈部出现无症状性进行性硬结短条索。根据临床和组织病理学检查结果诊断为硬斑病。在开始交替使用外用糖皮质激素和外用他克莫司后，她的病情有了临床改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/502941b8c71a/cureus-0016-00000073614-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/32df2e5ce68b/cureus-0016-00000073614-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/b8f4667ea897/cureus-0016-00000073614-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/502941b8c71a/cureus-0016-00000073614-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/32df2e5ce68b/cureus-0016-00000073614-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/b8f4667ea897/cureus-0016-00000073614-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d0/11642178/502941b8c71a/cureus-0016-00000073614-i03.jpg

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本文引用的文献

1
Morphea: The 2023 update.硬斑病：2023年更新版
Front Med (Lausanne). 2023 Feb 13;10:1108623. doi: 10.3389/fmed.2023.1108623. eCollection 2023.
2
Corrugated Indurated Short Cords on the Neck of a Teenage Girl.一名少女颈部的波纹状硬结短索
JAMA Dermatol. 2021 Apr 14. doi: 10.1001/jamadermatol.2021.0433.
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Lichen myxedematosus: a rare group of cutaneous mucinosis.黏液水肿性苔藓：一组罕见的皮肤黏蛋白病。
An Bras Dermatol. 2019 Oct 17;94(4):462-469. doi: 10.1590/abd1806-4841.20198478. eCollection 2019.
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European Dermatology Forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: localized scleroderma, systemic sclerosis and overlap syndromes.欧洲皮肤病论坛 S1 指南：皮肤硬化病的诊断和治疗，第 1 部分：局限性硬皮病、系统性硬皮病和重叠综合征。
J Eur Acad Dermatol Venereol. 2017 Sep;31(9):1401-1424. doi: 10.1111/jdv.14458. Epub 2017 Aug 9.
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Cordoniform morphea: a clinicopathologic study of two cases presenting with the rope sign.索状硬斑病：两例出现绳索征病例的临床病理研究
J Cutan Pathol. 2016 Jul;43(7):613-622. doi: 10.1111/cup.12704. Epub 2016 Apr 20.
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Histopathologic characteristics of scleromyxedema: A study of a series of 34 cases.硬皮黏液水肿的组织病理学特征：系列 34 例研究。
J Am Acad Dermatol. 2016 Jun;74(6):1194-200. doi: 10.1016/j.jaad.2015.12.021. Epub 2016 Feb 18.
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Pseudoxanthoma elasticum and skin: Clinical manifestations, histopathology, pathomechanism, perspectives of treatment.弹性假黄瘤与皮肤：临床表现、组织病理学、发病机制及治疗前景
Intractable Rare Dis Res. 2015 Aug;4(3):113-22. doi: 10.5582/irdr.2015.01014.
8
Nodular morphea (NM): report of a case of concurrent NM and morphea profunda associated with limited type systemic sclerosis, and overview and definition for NM.结节性硬斑病（NM）：同时患有 NM 和深部硬斑病、伴有限局性系统性硬皮病的病例报告，并对 NM 进行综述和定义。
Eur J Dermatol. 2013 Jan-Feb;23(1):87-93. doi: 10.1684/ejd.2012.1893.
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Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.肥厚性瘢痕和瘢痕疙瘩——关于其病理生理学、危险因素及治疗管理的综述
Dermatol Surg. 2009 Feb;35(2):171-81. doi: 10.1111/j.1524-4725.2008.34406.x.