Niklander Sven, Marín Constanza, Martínez René, Esguep Alfredo
DDS, MDent, MSc, Department of Oral Medicine and Oral Pathology, Universidad Andres Bello, Viña del Mar, Chile. Avenida Valparaíso 1560, Viña del Mar, Chile.
DDS, Department of Oral Medicine and Oral Pathology, Universidad Andres Bello, Viña del Mar, Chile. Avenida Valparaíso 1560, Viña del Mar, Chile.
J Clin Exp Dent. 2017 Feb 1;9(2):e315-e318. doi: 10.4317/jced.53151. eCollection 2017 Feb.
Morphea, or localized scleroderma, is an inflammatory disease that leads to sclerosis of the skin and underlying tissues due to excessive collagen deposition. Oral involvement is unusual and it may produce white linear fibrotic areas with a scar-like appearance, atrophy of tongue papillae, gingival recession and alveolar bone resorption. We report a case of a 13-year-old girl who consulted for progressive recession on the attached gingiva of her upper left incisors. She also presented a hypopigmented line on the left side skin of her upper lip, which continued through the vermilion and the lip mucosa, including the gingiva of the affected teeth. Clinical examination, blood tests, computerized axial tomography, echo-Doppler ultrasound and histopathological evaluation confirmed the diagnosis of morphea. Treatment with methotrexate and systemic corticosteroids was conducted. After 24 months, no other lesions appeared. No adverse side effects have been reported so far. Localized scleroderma, oral morphea, linear scleroderma, oral involvement, intraoral lesions.
硬斑病，即局限性硬皮病，是一种炎症性疾病，由于胶原蛋白过度沉积导致皮肤及皮下组织硬化。口腔受累情况并不常见，可能会产生白色线状纤维化区域，外观类似瘢痕，舌乳头萎缩、牙龈退缩及牙槽骨吸收。我们报告一例13岁女孩，因左上切牙附着龈渐进性退缩前来就诊。她在上唇左侧皮肤还有一条色素减退线，该线穿过唇红及唇黏膜，包括患牙的牙龈。临床检查、血液检查、计算机断层扫描、超声多普勒及组织病理学评估确诊为硬斑病。采用甲氨蝶呤和全身性皮质类固醇进行治疗。24个月后，未出现其他病变。目前尚未报告有不良反应。局限性硬皮病、口腔硬斑病、线状硬皮病、口腔受累、口腔内病变
