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治疗后[镥]镥-奥曲肽闪烁扫描中胆囊的偶然显影，酷似十二指肠神经内分泌肿瘤的肝转移。

Incidental Visualization of Gallbladder on Post-therapy [ Lu]Lu-DOTATATE Scintigraphy Mimicking a Liver Metastasis in a Duodenal Neuroendocrine Tumor.

作者信息

Baberwal Parth, Parghane Rahul, Basu Sandip

机构信息

Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.

Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

World J Nucl Med. 2024 Jul 4;23(4):292-294. doi: 10.1055/s-0044-1788073. eCollection 2024 Dec.

DOI:10.1055/s-0044-1788073
PMID:39677341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11637638/
Abstract

We present a rare case of physiological uptake of [ Lu]Lu-DOTATATE in the gallbladder, observed post-therapy, in a 47-year-old man with grade I duodenal neuroendocrine tumor (NET), despite no uptake being observed pre-therapy in the somatostatin receptor-positron emission tomography. On planar scintigraphy, the gallbladder uptake could have been misidentified as liver metastasis. By utilizing single photon emission computed tomography/computed tomography imaging, we were able to precisely localize the tracer and obtain anatomical morphological characteristics, thereby averting the potential for misinterpretation of liver metastasis resulting from the gallbladder's physiological uptake of [ Lu]Lu-DOTATATE in NET patients.

摘要

我们报告了一例罕见病例，一名47岁患有I级十二指肠神经内分泌肿瘤（NET）的男性患者，在接受[¹⁷⁷Lu]Lu-奥曲肽治疗后，胆囊出现了生理性摄取，尽管在治疗前的生长抑素受体正电子发射断层扫描中未观察到摄取情况。在平面闪烁扫描中，胆囊摄取可能会被误诊为肝转移。通过利用单光子发射计算机断层扫描/计算机断层扫描成像，我们能够精确地定位示踪剂并获得解剖形态特征，从而避免了因NET患者胆囊对[¹⁷⁷Lu]Lu-奥曲肽的生理性摄取而导致肝转移误诊的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2973/11637638/289c6f3beb70/10-1055-s-0044-1788073-i2450005-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2973/11637638/289c6f3beb70/10-1055-s-0044-1788073-i2450005-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2973/11637638/289c6f3beb70/10-1055-s-0044-1788073-i2450005-1.jpg

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