Gao Qian, Lin Yuanhong, Du Yan, Du Chi
Department of Oncology and Hematology, Dujiangyan People's Hospital, Chengdu, Sichuan, People's Republic of China.
Cancer Manag Res. 2024 Dec 10;16:1753-1758. doi: 10.2147/CMAR.S491295. eCollection 2024.
Sebaceous carcinoma (SC) is a rare malignancy and can be divided into two types, ocular and extra-ocular SC. Extra-ocular SC is typically associated with a better prognosis than ocular SC. However, extra-ocular SCs located in atypical areas, such as the inguinal region, along with multiple metastases, are uncommon and present significant challenges, often leading to poorer outcomes.
We present the case of a 68-year-old male patient who initially presented with a mass in the right inguinal region with multiple metastasis. A PET-CT scan revealed multiple enlarged lymph nodes and soft tissue masses in the abdominal and pelvic cavities. A biopsy confirmed the diagnosis of extra-ocular SC. Unfortunately, the disease progressed rapidly, and the patient succumbed to his illness just four months after diagnosis.
This case highlights the aggressive nature of extra-ocular SC in unusual locations, underscoring the necessity for heightened awareness and further research on this rare condition. Our findings contribute to a better understanding of extra-ocular SC and emphasize the urgent need for more investigation into optimal management strategies.
皮脂腺癌（SC）是一种罕见的恶性肿瘤，可分为两种类型，即眼型和眼外型皮脂腺癌。眼外型皮脂腺癌的预后通常比眼型皮脂腺癌更好。然而，位于非典型部位（如腹股沟区）且伴有多发转移的眼外型皮脂腺癌并不常见，且带来重大挑战，常常导致较差的预后。
我们报告一例68岁男性患者，最初表现为右侧腹股沟区肿物并伴有多发转移。PET-CT扫描显示腹部和盆腔内有多个肿大淋巴结及软组织肿物。活检确诊为眼外型皮脂腺癌。不幸的是，疾病进展迅速，患者在确诊仅四个月后就因病去世。
该病例突出了位于不寻常部位的眼外型皮脂腺癌的侵袭性，强调了提高对此罕见疾病的认识及进一步研究的必要性。我们的发现有助于更好地理解眼外型皮脂腺癌，并强调迫切需要对最佳治疗策略进行更多研究。
