Chen Po-Han, Chang Ruei-Je, Wang Hsiang-Sheng, Chang Ying-Hsu, Liu Chung-Yi, Huang Liang-Kang, Kan Hung-Chen, Lin Po-Hung, Yu Kai-Jie, Chuang Cheng-Keng, Pang See-Tong, Wu Chun-Te, Hsieh Ming-Li, Shao I-Hung
Medical Foundation, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan City, Taiwan.
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan City, Taiwan.
Clin Interv Aging. 2024 Dec 9;19:2071-2083. doi: 10.2147/CIA.S472579. eCollection 2024.
To investigate the impact of body mass index (BMI) on preoperative characteristics, lower urinary tract symptoms (LUTS), intraoperative variables, surgical outcomes and postoperative complications.
This is a retrospective observational study including 891 benign prostate hyperplasia (BPH) patients who underwent GreenLight Laser photoselective vaporization of the prostate (PVP) between 2014 and 2020. Clinical characteristics, uroflowmetry parameters, and surgery related parameters were extracted from electronic health records. Patients were categorized into different weight groups based on Taiwanese populations' BMI criteria. Statistical analyses, involving descriptive statistics, correlation analyses, and independent -tests, were employed to examine associations between BMI and relevant variables.
Pearson's correlation analysis indicated a negative correlation between BMI (r = -0.172, p < 0.001) and age, and positive correlations with total prostate volume (TPV) (r = 0.123, p < 0.001) and transition zone volume (TZV) (r = 0.083, p = 0.017). Obese patients were found to be younger (p=0.007) and have larger TPVs (p=0.010) but showed no significant differences in International Prostate Symptom Scores (IPSS) scores when compared to non-obese patients. Notably, obese patients had lower preoperative and postoperative post-void residual (PVR), whereas non-obese patients exhibited a more significant PVR reduction post-surgery. BMI did not significantly affect surgical parameters or postoperative complications.
In BPH patients treated with PVP, obese individuals were younger with larger prostates but had similar IPSS scores compared to non-obese patients. Obese patients had lower pre and post-surgery PVR, while non-obese patients saw greater PVR improvements. BMI plays a nuanced role BPH patients' characteristics.
探讨体重指数（BMI）对术前特征、下尿路症状（LUTS）、术中变量、手术结果及术后并发症的影响。
这是一项回顾性观察研究，纳入了2014年至2020年间接受绿激光选择性前列腺汽化术（PVP）的891例良性前列腺增生（BPH）患者。从电子健康记录中提取临床特征、尿流率参数和手术相关参数。根据台湾人群的BMI标准将患者分为不同体重组。采用描述性统计、相关性分析和独立检验等统计分析方法，研究BMI与相关变量之间的关联。
Pearson相关性分析表明，BMI与年龄呈负相关（r = -0.172，p < 0.001），与前列腺总体积（TPV）呈正相关（r = 0.123，p < 0.001），与移行区体积（TZV）呈正相关（r = 0.083，p = 0.017）。发现肥胖患者较年轻（p = 0.007）且TPV较大（p = 0.010），但与非肥胖患者相比，国际前列腺症状评分（IPSS）得分无显著差异。值得注意的是，肥胖患者术前和术后的残余尿量（PVR）较低，而非肥胖患者术后PVR下降更为显著。BMI对手术参数或术后并发症无显著影响。
在接受PVP治疗的BPH患者中，肥胖个体较年轻，前列腺较大，但与非肥胖患者的IPSS得分相似。肥胖患者术前和术后的PVR较低，而非肥胖患者的PVR改善更为明显。BMI在BPH患者特征中起微妙作用。
