Mehramiri Asieh, Heidari Mehrsa, Bahadoram Mohammad, Akade Esma'il
Department of Neurology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Medical Virology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Postep Psychiatr Neurol. 2024 Sep;33(3):196-200. doi: 10.5114/ppn.2024.144608. Epub 2024 Nov 5.
Sarcoidosis, a multi-organ granulomatous disease, occasionally involves the nervous system, presenting as neurosarcoidosis. The following case demonstrates a potential association between COVID-19 and brain and spinal cord injury mimicking neurosarcoidosis.
A 51-year-old woman presented with persistent holocranial headache, nausea, vertigo, and neurological deficits one month after a COVID-19 hospitalization. Neurological examination revealed hemiparesis, dysphagia, and ataxia. Imaging showed lesions in the central nervous system. A diagnosis of neurosarcoidosis was considered, supported by clinical criteria, imaging findings, and elevated ACE levels. Steroid therapy led to symptom improvement.
This case underscores the broad range of the consequences of COVID-19 and challenges in diagnosing neurosarcoidosis, suggesting the need for further research in this area.
结节病是一种多器官肉芽肿性疾病，偶尔累及神经系统，表现为神经结节病。以下病例展示了新型冠状病毒肺炎（COVID-19）与模仿神经结节病的脑和脊髓损伤之间的潜在关联。
一名51岁女性在COVID-19住院治疗一个月后出现持续性全颅头痛、恶心、眩晕和神经功能缺损。神经检查发现偏瘫、吞咽困难和共济失调。影像学检查显示中枢神经系统有病变。根据临床标准、影像学表现和血管紧张素转换酶（ACE）水平升高，考虑诊断为神经结节病。类固醇治疗使症状得到改善。
该病例强调了COVID-19后果的广泛范围以及诊断神经结节病的挑战，表明该领域需要进一步研究。
