Centre for Neurosarcoidosis, Neuroimmunology unit, Institute of Immunology and Transplantation, University College London, London, UK
Pract Neurol. 2020 May;20(3):199-212. doi: 10.1136/practneurol-2019-002349. Epub 2020 May 17.
Sarcoidosis affects the nervous system in 10% of cases. When it does so it can affect any part of the nervous system and with all degrees of severity. It forms part of the differential diagnosis in inflammatory, infective, neoplastic and degenerative neurological diseases and may be very difficult to diagnose without histological confirmation. Recent clinical studies and the increasing availability of new biological treatments allow a much clearer understanding of the disease. This review summarises its clinical features, imaging and laboratory characteristics, treatment and outcome.
结节病影响神经系统的概率为 10%。神经系统可能受到影响的部位和严重程度不一。在炎症、感染、肿瘤和退行性神经疾病的鉴别诊断中，结节病是其中之一，在没有组织学确认的情况下，其诊断可能非常困难。最近的临床研究和越来越多的新型生物治疗方法的出现，使我们对该病有了更清晰的认识。本文总结了其临床特征、影像学和实验室特征、治疗和预后。
