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病例报告:一例伴有多伊奇-波特综合征的胸膜巨大恶性孤立性纤维瘤并文献复习

Case report: A case of giant malignant solitary fibrous tumor of the pleura with Doege-Potter's syndrome and review of the literature.

作者信息

Li Jie, Tang Hong-Tao, Liu Qing, Li Cai-Han, Chen Wei-Yang, Yu Zeng-Wei, Wang Lei, Lin Lin, Zhao Jin-Lan, Zhao Chun-Yan, Chen Long-Qi, Tian Dong

机构信息

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Front Oncol. 2024 Nov 29;14:1437535. doi: 10.3389/fonc.2024.1437535. eCollection 2024.

Abstract

The solitary fibrous tumor of the pleura (SFTP) is a rare intrathoracic neoplasm that commonly originates from the subpleural mesenchymal cells of the visceral pleura and accounts for less than 5% of all pleural tumors. We reported a case of a 54-year-old man with a two-week history of hypoglycemia, a six-month history of productive cough and fatigue, and chronic right chest pain. Radiological techniques revealed a giant intra-thoracic mass with hypervascularization, and pathological staining was carried out to make a definitive diagnosis of SFTP. Interventional embolization was conducted to block the main feeding vessels before the surgery, and an anterolateral thoracotomy combined with a transverse sternotomy was performed to achieve a complete resection, which demonstrates significant potential for further application in patients with unilateral giant SFTP. The postoperative course was uneventful, with no signs of hypoglycemia observed during the follow-up. Additionally, we reviewed and prospected the research progress on SFTP. The aim of this study is to enhance clinicians' understanding of SFTP through our case and to provide a detailed review of the current research.

摘要

胸膜孤立性纤维瘤(SFTP)是一种罕见的胸内肿瘤,通常起源于脏层胸膜的胸膜下间充质细胞,占所有胸膜肿瘤的比例不到5%。我们报告了一例54岁男性病例,患者有两周的低血糖病史、六个月的咳痰和疲劳病史以及慢性右胸痛。放射学检查发现一个巨大的胸内肿块,伴有血管增多,进行了病理染色以明确诊断为SFTP。在手术前进行了介入栓塞以阻断主要供血血管,并实施了前外侧开胸术联合横断胸骨切开术以实现完整切除,这显示出在单侧巨大SFTP患者中进一步应用的巨大潜力。术后过程顺利,随访期间未观察到低血糖迹象。此外,我们回顾并展望了SFTP的研究进展。本研究的目的是通过我们的病例增强临床医生对SFTP的认识,并对当前研究进行详细综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f7/11638045/155616a3d246/fonc-14-1437535-g001.jpg

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