Li Jie, Tang Hong-Tao, Liu Qing, Li Cai-Han, Chen Wei-Yang, Yu Zeng-Wei, Wang Lei, Lin Lin, Zhao Jin-Lan, Zhao Chun-Yan, Chen Long-Qi, Tian Dong
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Front Oncol. 2024 Nov 29;14:1437535. doi: 10.3389/fonc.2024.1437535. eCollection 2024.
The solitary fibrous tumor of the pleura (SFTP) is a rare intrathoracic neoplasm that commonly originates from the subpleural mesenchymal cells of the visceral pleura and accounts for less than 5% of all pleural tumors. We reported a case of a 54-year-old man with a two-week history of hypoglycemia, a six-month history of productive cough and fatigue, and chronic right chest pain. Radiological techniques revealed a giant intra-thoracic mass with hypervascularization, and pathological staining was carried out to make a definitive diagnosis of SFTP. Interventional embolization was conducted to block the main feeding vessels before the surgery, and an anterolateral thoracotomy combined with a transverse sternotomy was performed to achieve a complete resection, which demonstrates significant potential for further application in patients with unilateral giant SFTP. The postoperative course was uneventful, with no signs of hypoglycemia observed during the follow-up. Additionally, we reviewed and prospected the research progress on SFTP. The aim of this study is to enhance clinicians' understanding of SFTP through our case and to provide a detailed review of the current research.
胸膜孤立性纤维瘤(SFTP)是一种罕见的胸内肿瘤,通常起源于脏层胸膜的胸膜下间充质细胞,占所有胸膜肿瘤的比例不到5%。我们报告了一例54岁男性病例,患者有两周的低血糖病史、六个月的咳痰和疲劳病史以及慢性右胸痛。放射学检查发现一个巨大的胸内肿块,伴有血管增多,进行了病理染色以明确诊断为SFTP。在手术前进行了介入栓塞以阻断主要供血血管,并实施了前外侧开胸术联合横断胸骨切开术以实现完整切除,这显示出在单侧巨大SFTP患者中进一步应用的巨大潜力。术后过程顺利,随访期间未观察到低血糖迹象。此外,我们回顾并展望了SFTP的研究进展。本研究的目的是通过我们的病例增强临床医生对SFTP的认识,并对当前研究进行详细综述。