Dole Sachinkumar, Gupta Samir, Barthwal M S, Ramesh Ashwin
Professor (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth University, Pune, India.
Professor & Head (Surgical Uncology), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth University, Pune, India.
Med J Armed Forces India. 2024 Dec;80(Suppl 1):S333-S336. doi: 10.1016/j.mjafi.2023.12.004. Epub 2024 Jan 16.
Solitary fibrous tumors of pleura (SFTP) are rare neoplasms derived from mesenchymal cells of the pleura. A 63-year-old male patient, laborer by profession, presented with progressive dry cough and breathlessness for one month. Clinically he had left-sided intrathoracic mass which was confirmed by CT thorax. While in hospital, patient had recurrent episodes of hypoglycemia. Histopathological examination and immunohistochemistry of the mass revealed a SFTP. Complete surgical resection of the mass led to left lung expansion and post-operative stay was uneventful. Patient was discharged with advice for follow-up. When SFTPs are associated with recurrent hypoglycemia, which is caused by the secretion of a high-molecular-weight insulin-like growth factor 2 (IGF-2), it is referred to as the Doege-Potter syndrome (DPS).
胸膜孤立性纤维瘤(SFTP)是起源于胸膜间充质细胞的罕见肿瘤。一名63岁男性患者,职业为工人,出现进行性干咳和气短1个月。临床检查发现他有左侧胸腔内肿块,胸部CT证实了这一点。住院期间,患者反复出现低血糖发作。对肿块进行组织病理学检查和免疫组化显示为SFTP。肿块的完整手术切除使左肺得以扩张,术后恢复顺利。患者出院时被告知要进行随访。当SFTP与反复低血糖相关时,这是由高分子量胰岛素样生长因子2(IGF-2)的分泌引起的,被称为多伊格-波特综合征(DPS)。