Cheng Weipo, Zhou Jianping, Li Chan, Yao Jingrun, Zhang Xiaoqing, Mao Fangyuan, Gao Zhirui, Jiang Lei, Xu Haizhou
Department of Cardiovascular Medicine, Changhai Hospital Affiliated to Naval Medical University Shanghai 200433, The People's Republic of China.
Department of Emergency, Changhai Hospital Affiliated to Naval Medical University Shanghai 200433, The People's Republic of China.
Am J Transl Res. 2024 Nov 15;16(11):6821-6827. doi: 10.62347/CBMB4249. eCollection 2024.
is an obligate aerobic, Gram-negative bacillus belonging to the family of Weeksellacease. In recent years, there has been a gradual increase in related infections, especially in chronically hospitalized, immunocompromised populations that often develop severe pneumonia. Severe pneumonia is one of the common critical illnesses. Next-generation sequencing technologies developed based on PCR and gene chip technologies play an important role in the identification of pathogenic microorganisms and in molecular diagnosis. In this case, we report an elderly male patient diagnosed with severe pneumonia during the COVID-19 pandemic. The causative organisms were clearly identified as combined with by next-generation sequencing. He was discharged from the hospital after being given cefoperazone sulbactam sodium and minocycline, as well as nebulized inhalation of chymotrypsin, salbutamol, and budesonide to assist ventilation. This article summarizes the diagnosis and treatment of this patient in order to share the experience of the subsequent treatments.
是一种专性需氧的革兰氏阴性杆菌,属于韦荣氏菌科。近年来,相关感染呈逐渐上升趋势,尤其是在长期住院的免疫功能低下人群中,这类人群常发展为重症肺炎。重症肺炎是常见的危重症之一。基于PCR和基因芯片技术开发的下一代测序技术在病原微生物鉴定和分子诊断中发挥着重要作用。在此病例中,我们报告了一名在新冠疫情期间被诊断为重症肺炎的老年男性患者。通过下一代测序明确鉴定出致病微生物为 与 合并感染。给予头孢哌酮舒巴坦钠和米诺环素治疗,同时雾化吸入糜蛋白酶、沙丁胺醇和布地奈德以辅助通气后,患者出院。本文总结了该患者的诊断和治疗过程,以便分享后续治疗经验。