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前交叉韧带重建手术中使用腘绳肌腱与股四头肌肌腱移植物及髌腱的临床结果比较:一项随机临床试验

Comparison of Clinical Results Using Hamstring Versus Quadriceps Tendon Graft Versus Bone Patella Tendon in Anterior Cruciate Ligament Reconstruction Surgery: A Randomized Clinical Trial.

作者信息

Fallah Ehsan, Naghshbandi Mobin, Ghafoury Roya, Hosseini Zare Nima

机构信息

Clinical Biomechanics and Ergonomics Research Center, Aja University of Medical Sciences, Tehran, Iran.

School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Med J Islam Repub Iran. 2024 Jul 10;38:79. doi: 10.47176/mjiri.38.79. eCollection 2024.

DOI:10.47176/mjiri.38.79
PMID:39678774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11644201/
Abstract

BACKGROUND

Anterior cruciate ligament (ACL) reconstruction is pivotal for restoring knee stability and function in individuals with ACL injuries. While bone-patellar tendon-bone (PT), hamstring tendon (HT), and quadriceps tendon (QT) autografts are commonly employed, their comparative effectiveness remains a subject of ongoing research. This study aims to comprehensively compare the functional outcomes, knee stability, revision rates, and incidence of anterior knee pain associated with these autografts.

METHODS

In this randomized clinical trial, adult male participants undergoing primary single-bundle ACL reconstruction were randomized into three groups (PT, HT, QT) using a computer-generated sequence with allocation concealment. Blinded assessments were conducted at 2-, 6-, and 12-months post-surgery to evaluate knee function, stability, and patient satisfaction. The rehabilitation protocol was standardized across groups, including specific exercises and cryotherapy, to minimize postoperative swelling and pain.

RESULTS

A total of 75 participants were followed for 12 months post-surgery. While significant improvements in knee function and stability were observed across all groups, there were no statistically significant differences between the autograft types in terms of revision rates or the incidence of anterior knee pain. Detailed statistical analysis revealed effect sizes and confidence intervals, substantiating the clinical relevance of the findings.

CONCLUSION

PT, HT, and QT autografts each provide favorable outcomes for ACL reconstruction without significant differences in efficacy up to one year postoperatively.Level of Evidence: Level 2 (Randomized Clinical Trial).

摘要

背景

前交叉韧带(ACL)重建对于恢复ACL损伤患者的膝关节稳定性和功能至关重要。虽然骨-髌腱-骨(PT)、腘绳肌腱(HT)和股四头肌肌腱(QT)自体移植物被广泛应用,但其相对有效性仍是正在进行的研究课题。本研究旨在全面比较这些自体移植物相关的功能结果、膝关节稳定性、翻修率和前膝痛发生率。

方法

在这项随机临床试验中,接受初次单束ACL重建的成年男性参与者使用计算机生成的序列并采用分配隐藏随机分为三组(PT、HT、QT)。在术后2个月、6个月和12个月进行盲法评估,以评估膝关节功能、稳定性和患者满意度。各小组的康复方案标准化,包括特定锻炼和冷冻疗法,以尽量减少术后肿胀和疼痛。

结果

共75名参与者术后随访12个月。虽然所有组膝关节功能和稳定性均有显著改善,但自体移植物类型在翻修率或前膝痛发生率方面无统计学显著差异。详细的统计分析显示了效应大小和置信区间,证实了研究结果的临床相关性。

结论

PT、HT和QT自体移植物在ACL重建中均能提供良好结果,术后一年内在疗效上无显著差异。证据级别:2级(随机临床试验)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf49/11644201/f7423cd9e262/mjiri-38-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf49/11644201/a6a4852aec2f/mjiri-38-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf49/11644201/f7423cd9e262/mjiri-38-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf49/11644201/a6a4852aec2f/mjiri-38-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf49/11644201/f7423cd9e262/mjiri-38-79-g002.jpg

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本文引用的文献

1
The Risk Factors and Preventive Strategies of Poor Knee Functions and Osteoarthritis after Anterior Cruciate Ligament Reconstruction: A Narrative Review.前交叉韧带重建术后膝关节功能不佳及骨关节炎的危险因素与预防策略:一项叙述性综述
Phys Ther Res. 2023;26(3):78-88. doi: 10.1298/ptr.R0028. Epub 2023 Nov 25.
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Medial Patellofemoral Ligament Reconstruction Using Pedicled Quadriceps Tendon Autograft Yields Similar Clinical and Patient-Reported Outcomes but Less Donor-Site Morbidity Compared With Gracilis Tendon Autograft.采用带蒂股四头肌肌腱自体移植物进行内侧髌股韧带重建术与采用股薄肌腱自体移植物相比,具有相似的临床和患者报告结果,但供体部位发病率较低。
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Functional Anterior Knee Pain and Return to Sport Following Bone-Patellar Tendon-Bone Anterior Cruciate Ligament Reconstruction.
髌腱-骨前交叉韧带重建术后的功能性前膝痛与恢复运动情况
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Quadriceps tendon autograft is comparable to hamstring tendon and bone-patella-tendon-bone up to 2 years after isolated primary anterior cruciate ligament reconstruction.在单独进行初次前交叉韧带重建术后 2 年内,股四头肌腱自体移植物的效果可与腘绳肌腱和骨-髌腱-骨相媲美。
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