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儿童发育性髋关节发育不良超声检查后常规X线监测的效用:一项为期十年的单中心研究

Utility of routine X-ray surveillance following hip sonography for developmental dysplasia in children: a single-center study spanning a decade.

作者信息

Wolf Matthias, Haas Leon, Tsitlakidis Stefanos, Deisenhofer Julian, Horsch Axel, Hagmann Sébastien, Gather Katharina Susanne

机构信息

Klinik für Orthopädie, Universitätsklinikum Heidelberg, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.

Deutsches Gelenkzentrum Heidelberg, ATOS Klinik Heidelberg, Bismarckstr. 9-15, 69115, Heidelberg, Germany.

出版信息

Arch Orthop Trauma Surg. 2024 Dec 16;145(1):41. doi: 10.1007/s00402-024-05695-7.

Abstract

INTRODUCTION

This study evaluates the necessity of routine X-ray follow-ups in children with developmental dysplasia of the hip (DDH), identified through Graf hip ultrasound, a standard component of screening in Germany. The purpose of this study was to investigate the occurrence of radiological deterioration in hips that were initially diagnosed and treated according to established guidelines within a university-based risk-enriched cohort and to identify associated risk factors.

MATERIALS AND METHODS

Patients diagnosed with developmental DDH from 2009 to 2018 with sonographically healthy hips (alpha > 64°) post conservative therapy and at least one follow-up X-ray by the age of two were analysed. Patients with significant comorbidities, syndromes, malformations, non-compliance with treatment, or missing X-ray data were excluded. Descriptive analysis of sonography, X-ray, and patient records were followed by univariate analysis and subsequent multiple logistic regression, identifying risk factors for severe and extreme dysplasia in X-rays.

RESULTS

Of the 450 included hips, 254 were classified as Graf Type 2a or higher, leading to treatment. Subsequent X-rays revealed severe dysplasia in 53 hips and extreme dysplasia in seven hips. Univariate analysis identified sex, initial Graf-Type, therapy type and duration as significantly associated with pathological radiographs. A regression model identified the initial Graf type as the predominant predictor with hip types 3a and 4, cast therapy and overhead extension as independent predictors.

CONCLUSIONS

The data demonstrate pathological findings even after successful conservative treatment of DDH. Worsening of X-ray findings appear less frequent in mild dysplasia. These insights support routine radiographic follow-up assessments after successful conservative therapy. However, further dedicated studies are needed to determine whether patients with initially normal radiographs require radiographic follow-up.

摘要

引言

本研究评估了在德国作为筛查标准组成部分的Graf髋关节超声检查发现的发育性髋关节发育不良(DDH)患儿进行常规X线随访的必要性。本研究的目的是调查在一个基于大学的高风险队列中,最初根据既定指南诊断和治疗的髋关节出现放射学恶化的情况,并确定相关的风险因素。

材料与方法

分析2009年至2018年诊断为发育性DDH且保守治疗后超声检查髋关节健康(α>64°)且两岁前至少有一次随访X线检查的患者。排除有严重合并症、综合征、畸形、不遵守治疗或缺少X线数据的患者。对超声、X线和患者记录进行描述性分析,随后进行单因素分析和多因素逻辑回归,确定X线检查中严重和极重度发育不良的风险因素。

结果

在纳入的450个髋关节中,254个被分类为Graf 2a型或更高,需要治疗。随后的X线检查显示53个髋关节有严重发育不良,7个髋关节有极重度发育不良。单因素分析确定性别、初始Graf类型、治疗类型和持续时间与病理性X线片显著相关。回归模型确定初始Graf类型是主要预测因素,3a型和4型髋关节、石膏治疗和头端伸展是独立预测因素。

结论

数据表明,即使DDH成功保守治疗后仍有病理表现。轻度发育不良中X线表现恶化的情况似乎较少见。这些见解支持成功保守治疗后进行常规X线随访评估。然而,需要进一步的专门研究来确定最初X线片正常的患者是否需要进行X线随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4928/11649832/c175747fa4bc/402_2024_5695_Fig1_HTML.jpg

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