Lee Yoon Li Madeline, Lee Si Min Stephanie, Sündermann Oliver
National University of Singapore, Singapore, Singapore.
JMIR Mhealth Uhealth. 2024 Dec 16;12:e63316. doi: 10.2196/63316.
Obsessive-compulsive disorder (OCD) is the third most prevalent mental health disorder in Singapore, with a high degree of burden and large treatment gaps. Self-guided programs on mobile apps are accessible and affordable interventions, with the potential to address subclinical OCD before symptoms escalate.
This randomized controlled trial aimed to examine the efficacy of a self-guided OCD program on the mobile health (mHealth) app Intellect in improving subclinical OCD and maladaptive perfectionism (MP) as a potential moderator of this predicted relationship.
University students (N=225) were randomly assigned to an 8-day, self-guided app program on OCD (intervention group) or cooperation (active control). Self-reported measures were obtained at baseline, after the program, and at a 4-week follow-up. The primary outcome measure was OCD symptom severity (Obsessive Compulsive Inventory-Revised [OCI-R]). Baseline MP was assessed as a potential moderator. Depression, anxiety, and stress (Depression Anxiety and Stress Scales-21) were controlled for during statistical analyses.
The final sample included 192 participants. The intervention group reported significantly lower OCI-R scores compared with the active control group after the intervention (partial eta-squared [η]=0.031; P=.02) and at 4-week follow-up (η=0.021; P=.044). A significant, weak positive correlation was found between MP and OCI-R levels at baseline (r=0.28; P<.001). MP was not found to moderate the relationship between condition and OCI-R scores at postintervention (P=.70) and at 4-week follow-up (P=.88).
This study provides evidence that the self-guided OCD program on the Intellect app is effective in reducing subclinical OCD among university students in Singapore. Future studies should include longer follow-up durations and study MP as a moderator in a broader spectrum of OCD symptom severity.
ClinicalTrials.gov NCT06202677; https://clinicaltrials.gov/study/NCT06202677.
强迫症（OCD）是新加坡第三大常见的心理健康障碍，负担程度高且治疗差距大。移动应用程序上的自我引导项目是可获取且经济实惠的干预措施，有潜力在症状升级前解决亚临床强迫症问题。
这项随机对照试验旨在检验移动健康（mHealth）应用程序Intellect上的一个自我引导强迫症项目在改善亚临床强迫症和适应不良完美主义（MP）方面的效果，MP作为这种预测关系的潜在调节因素。
大学生（N = 225）被随机分配到一个为期8天的关于强迫症的自我引导应用程序项目（干预组）或合作项目（积极对照组）。在基线、项目结束后以及4周随访时获取自我报告测量数据。主要结局指标是强迫症症状严重程度（强迫症量表修订版[OCI-R]）。基线MP被评估为潜在调节因素。在统计分析过程中对抑郁、焦虑和压力（抑郁焦虑压力量表-21）进行了控制。
最终样本包括192名参与者。干预组在干预后（偏η方[η]=0.031；P = 0.02）和4周随访时（η = 0.021；P = 0.044）报告的OCI-R得分显著低于积极对照组。在基线时，MP与OCI-R水平之间发现显著的弱正相关（r = 0.28；P < 0.001）。在干预后（P = 0.70）和4周随访时（P = 0.88），未发现MP调节条件与OCI-R得分之间的关系。
本研究提供了证据，表明Intellect应用程序上的自我引导强迫症项目在降低新加坡大学生的亚临床强迫症方面是有效的。未来的研究应包括更长的随访期，并在更广泛的强迫症症状严重程度范围内研究MP作为调节因素。
ClinicalTrials.gov NCT06202677；https://clinicaltrials.gov/study/NCT06202677 。
