Fitzgerald R H, Ruttle P E, Arnold P G, Kelly P J, Irons G B
J Bone Joint Surg Am. 1985 Feb;67(2):175-85.
When large soft-tissue and osseous defects remain after débridement of a chronic osteomyelitic lesion, application of a local muscle flap can be an effective way to achieve wound closure. Utilizing this surgical technique and specific antimicrobial therapy for the causal microorganisms, the infectious process was eradicated in thirty-nine of forty-two patients with osteomyelitis who were followed for at least two years after treatment. The osteomyelitic process was post-traumatic in origin--that is, a complication of a fracture or its treatment--in twenty-eight patients, the result of soft-tissue trauma without a fracture in eight, a complication of elective surgery in three, and the result of hematogenous seeding in three patients. Nine of the forty-two patients had an infected non-union. The infectious process involved the tibia in 62 per cent of the patients. Pseudomonas aeruginosa was the most frequently isolated causal organism. A soleus or gastrocnemius muscle flap was most frequently utilized to achieve closure. In five patients, a combination of two muscle flaps was utilized. Although this technique successfully eradicated the infectious process in 93 per cent of the patients, twenty-two patients required additional surgical treatment. Six required such treatment for a persistent non-union and two, for weakened diaphyseal bone after eradication of the septic process. A cancellous bone-grafting procedure was performed in all eight patients after the muscle flap had healed, and union was achieved in six of them. One patient eventually requested an amputation for a persistent non-union, and the remaining patient had a fibular synostosis performed for a persistent tibial non-union. A local muscle flap can be used in patients with a large defect of soft tissue and bone after débridement of an osteomyelitic lesion if the flap can be elevated and transposed into the defect without compromising its vascular supply. Although they are not applicable to the treatment of all patients with osteomyelitis, local muscle flaps can be extremely useful in the treatment of this lesion. When combined with thorough débridement and specific antimicrobial therapy, it has become a successful technique in the management of chronic osteomyelitis.
对慢性骨髓炎病灶进行清创后若仍存在较大的软组织和骨缺损,应用局部肌瓣是实现伤口闭合的有效方法。采用这种手术技术并针对致病微生物进行特异性抗菌治疗,在42例骨髓炎患者中,有39例在治疗后至少随访两年时感染过程得以根除。骨髓炎病程起源于创伤后,即骨折或其治疗的并发症,其中28例患者如此;8例为无骨折的软组织创伤所致;3例为择期手术的并发症;3例为血行播散所致。42例患者中有9例存在感染性骨不连。62%的患者感染过程累及胫骨。铜绿假单胞菌是最常分离出的致病微生物。最常采用比目鱼肌或腓肠肌肌瓣来实现伤口闭合。5例患者采用了两种肌瓣联合应用。尽管该技术成功根除了93%患者的感染过程,但仍有22例患者需要额外的手术治疗。6例因持续性骨不连需要此类治疗,2例因感染过程根除后骨干骨质薄弱需要治疗。在肌瓣愈合后,所有8例患者均进行了松质骨移植手术,其中6例实现了骨愈合。1例患者最终因持续性骨不连要求截肢,其余1例患者因持续性胫骨骨不连进行了腓骨融合术。如果能在不影响其血供的情况下将肌瓣掀起并转移至缺损处,局部肌瓣可用于骨髓炎病灶清创后存在较大软组织和骨缺损的患者。尽管它们并不适用于所有骨髓炎患者,但局部肌瓣在这种疾病的治疗中可能极为有用。当与彻底清创和特异性抗菌治疗相结合时,它已成为治疗慢性骨髓炎的一种成功技术。