Wei Renjie, Liu Fudong, Luo Xu, Gong Chunyu, Ran Ruitu
Department of Urology and Pelvic surgery, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Int J Immunopathol Pharmacol. 2024 Jan-Dec;38:3946320241307777. doi: 10.1177/03946320241307777.
Tubulocystic Renal Cell Carcinoma (TC-RCC) and Polycythemia Vera (PV) are both infrequent medical conditions. TC-RCC was recognized as a distinct subtype of kidney cancer by the World Health Organization in 2016, while PV is a rare myeloproliferative neoplasm distinguished by the excessive production of red blood cells. The coexistence of these two conditions is exceptionally uncommon and lacks comprehensive documentation. This study presents a case report of a 35-year-old male patient who has been diagnosed with PV for the past 20 years. The patient underwent a radical nephrectomy to remove the renal tumor, and subsequent histopathological analysis confirmed the presence of TC-RCC. Throughout the 6-month follow-up period, the patient exhibited no signs of abnormalities. The rarity of the coexistence of TC-RCC and PV highlights the intricate nature of managing such instances, necessitating a cautious approach to diagnosis and treatment, particularly in surgical interventions. The present study serves as a valuable resource for diagnosing and treating individuals presenting with concurrent renal neoplasms and PV.
管状囊性肾细胞癌（TC-RCC）和真性红细胞增多症（PV）都是罕见的病症。TC-RCC于2016年被世界卫生组织认定为一种独特的肾癌亚型，而PV是一种罕见的骨髓增殖性肿瘤，其特征是红细胞过度生成。这两种病症同时存在极为罕见，且缺乏全面的文献记载。本研究报告了一名35岁男性患者的病例，该患者在过去20年中被诊断为PV。患者接受了根治性肾切除术以切除肾脏肿瘤，随后的组织病理学分析证实存在TC-RCC。在6个月的随访期内，患者未表现出异常迹象。TC-RCC和PV同时存在的罕见性凸显了处理此类病例的复杂性，需要谨慎的诊断和治疗方法，尤其是在手术干预方面。本研究为诊断和治疗同时患有肾肿瘤和PV的个体提供了宝贵的参考资料。
