Najean Y
Département de Médecine Nucléaire, Hôpital Saint-Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1991;33(1):9-10.
In a series of 300 cases of PV evaluated and treated over the last 12 years, 5 cases had a kidney carcinoma, either previously treated (2 cases) or discovered at the same time as the PV (3 cases). In all these cases, the blood disease had the criteria of a myeloproliferative syndrome (abnormality of three cell-lines), was not influenced by nephrectomy and evolved in the long term like a primary PV. No kidney cancer was observed during follow-up of the other 32P treated PV patients. There appears to be an abnormal association between PV and kidney cancer which needs confirmation in larger series and would justify a prospective evaluation.
在过去12年里评估和治疗的300例真性红细胞增多症患者中，有5例患有肾癌，其中2例为既往已治疗的肾癌，3例为与真性红细胞增多症同时发现的肾癌。在所有这些病例中，血液疾病符合骨髓增殖综合征的标准（三种细胞系异常），不受肾切除术的影响，并且长期演变过程类似原发性真性红细胞增多症。在其他接受32P治疗的真性红细胞增多症患者的随访中未观察到肾癌。真性红细胞增多症与肾癌之间似乎存在异常关联，这需要在更大规模的病例系列中得到证实，并且有必要进行前瞻性评估。
