Long Shenfei, Mahfuz Shad, Piao Xiangshu
Beijing Jingwa Agricultural Science and Technology Innovation Center, Beijing 101205, China.
State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Animals (Basel). 2024 Nov 23;14(23):3378. doi: 10.3390/ani14233378.
In this study, the aim was to evaluate the effects of dietary 25-hydroxycholecalciferol supplementation from day 85 of gestation on performance, antioxidant capacity, and immunoglobulin level of sows and newborn piglets. On day 85 of gestation, forty Landrace × Yorkshire gestating sows (average body weight of 241 ± 6.8 kg; average parity of 3.47 ± 0.6) were allotted into two treatments (20 replicates per treatment) based on parity, body weight, and back fat thickness. From day 85 of gestation to farrowing, sows were fed a normal vitamin D diet as control (containing 50 μg/kg vitamin D; CON), or a 25-hydroxycholecalciferol-supplemented diet (containing 50 μg/kg 25-hydroxycholecalciferol). Compared with CON, dietary 25-hydroxycholecalciferol supplementation increased ( < 0.05) protein and fat content in colostrum and the average birth body weight of newborn piglets. Sows fed 25-hydroxycholecalciferol showed increased ( < 0.05) apparent total tract digestibility of crude protein compared with CON. Diets supplemented with 25-hydroxycholecalciferol also increased ( < 0.05) the content of superoxide dismutase (SOD), and tended to increase ( = 0.06) the total antioxidant capacity content and reduce ( = 0.09) the malondialdehyde (MDA) level in colostrum. An increase ( < 0.05) in the content of SOD and a reduction ( < 0.05) in the content of MDA in the serum of newborn piglets was also observed in the 25-hydroxycholecalciferol treatment compared with CON. Dietary 25-hydroxycholecalciferol supplementation also enhanced ( < 0.05) the immunoglobulin G content and reduced ( < 0.05) the concentration of tumor nuclear factor-α in the serum of sows, as well as reducing ( < 0.05) the content of immunoglobulin G and immunoglobulin A in the serum of newborn piglets compared with CON. Supplementation of 25-hydroxycholecalciferol in sow diets increased ( < 0.05) the content of alkaline phosphatase in the serum and colostrum of sows, the concentration of insulin and crosslap in serum of sows, and the serum calcium content of newborn piglets compared with CON. In conclusion, dietary 25-hydroxycholecalciferol supplementation from day 85 of gestation could enhance performance, antioxidant capacity, and immunoglobulin in sows and newborn piglets.
在本研究中，目的是评估从妊娠第85天开始日粮添加25-羟基胆钙化醇对母猪和新生仔猪生产性能、抗氧化能力及免疫球蛋白水平的影响。在妊娠第85天，将40头长白×大白妊娠母猪（平均体重241±6.8 kg；平均胎次3.47±0.6）根据胎次、体重和背膘厚度分为两个处理组（每个处理20个重复）。从妊娠第85天至分娩，母猪饲喂正常维生素D日粮作为对照（含50 μg/kg维生素D；CON），或饲喂添加25-羟基胆钙化醇的日粮（含50 μg/kg 25-羟基胆钙化醇）。与CON组相比，日粮添加25-羟基胆钙化醇提高了（P<0.05）初乳中蛋白质和脂肪含量以及新生仔猪的平均出生体重。饲喂25-羟基胆钙化醇的母猪与CON组相比，粗蛋白的表观全肠道消化率提高了（P<0.05）。添加25-羟基胆钙化醇的日粮还提高了（P<0.05）初乳中超氧化物歧化酶（SOD）的含量，并趋于提高（P = 0.06）总抗氧化能力含量和降低（P = 0.09）丙二醛（MDA）水平。与CON组相比，25-羟基胆钙化醇处理组新生仔猪血清中SOD含量增加（P<0.05），MDA含量降低（P<0.05）。日粮添加25-羟基胆钙化醇还提高了（P<0.05）母猪血清中免疫球蛋白G含量并降低了（P<0.05）肿瘤核因子-α浓度，同时与CON组相比降低了（P<0.05）新生仔猪血清中免疫球蛋白G和免疫球蛋白A的含量。与CON组相比，在母猪日粮中添加25-羟基胆钙化醇提高了（P<0.05）母猪血清和初乳中碱性磷酸酶的含量、母猪血清中胰岛素和交联蛋白的浓度以及新生仔猪的血清钙含量。总之，从妊娠第85天开始日粮添加25-羟基胆钙化醇可提高母猪和新生仔猪的生产性能、抗氧化能力及免疫球蛋白水平。
