Preda Marius, Kundnani Nilima Rajpal, Buzas Roxana, Dema Sorin, Carabineanu Adrian, Miclaus Codruta Dana, Ilina Razvan, Cretu Octavian Marius, Blidisel Alexandru
Second Discipline of Surgical Semiology, Department IX-Surgery-1, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Second Clinic of General Surgery and Surgical Oncology, Emergency Clinical Municipal Hospital, 300079 Timișoara, Romania.
Diagnostics (Basel). 2024 Nov 29;14(23):2699. doi: 10.3390/diagnostics14232699.
Accessory breast cancer cases are rarely reported in the literature. Of the reported cases, the predominantly available ones are those localized in the axillary region. We present here a very rare case of metastatic accessory breast cancer. It was located in the infra-mammary region (IMR). IMR accessory breast cancer is a rare form of breast cancer. Although ectopic nipples are occasionally found in the IMR, because of the lack of ductal tissue malignant changes, they are rare. In our case, the primary tumor was localized in the congenital accessory breast tissue (ABT). It was recognized as invasive lobular accessory breast cancer cT3N1M0 with a second NST carcinoma, cT2N0M0, Stage IIA, in the ipsilateral breast. A multi-modal approach was applied. Adjuvant chemotherapy was carried out with epirubicin, cyclophosphamide, and paclitaxel, with post-chemotherapy ultrasound followed by right radical mastectomy. Adjuvant radiotherapy was given to our patient in the form of 25 fractions of 50 GY for 25 days, followed by hormonal treatment with Letrozole, 2.5 mg/day, to be continued for 5 years. our case demonstrates that since it is rare to find accessory breast cancer in the infra-mammary region, early identification and management with a multi-modal approach can lead to a successful patient outcome.
副乳腺癌病例在文献中鲜有报道。在已报道的病例中，主要是那些位于腋窝区域的病例。我们在此呈现一例极为罕见的转移性副乳腺癌病例。它位于乳房下区域（IMR）。IMR副乳腺癌是一种罕见的乳腺癌形式。尽管在IMR偶尔会发现异位乳头，但由于缺乏导管组织的恶性变化，它们很罕见。在我们的病例中，原发肿瘤位于先天性副乳腺组织（ABT）中。它被诊断为浸润性小叶副乳腺癌cT3N1M0，同时同侧乳房有第二个非特殊类型癌，cT2N0M0，IIA期。采用了多模式治疗方法。使用表柔比星、环磷酰胺和紫杉醇进行辅助化疗，化疗后进行超声检查，随后行右侧根治性乳房切除术。给予患者辅助放疗，以25次、每次50GY、共25天的方式进行，随后给予来曲唑进行激素治疗，剂量为2.5mg/天，持续5年。我们的病例表明，由于在乳房下区域发现副乳腺癌很罕见，早期识别并采用多模式治疗方法可以使患者获得成功的治疗结果。
