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创伤患者的医院获得性细菌性支气管肺炎和新型冠状病毒肺炎:肺组织的影像学表现以及大体和微观发现

Nosocomial Bacterial Bronchopneumonia and SARS-CoV-2 Pneumonia in Patients with Traumatic Injuries: Imaging Aspects and Macroscopic and Microscopic Findings of Lung Tissue.

作者信息

Gavriliţă Georgiana-Denisa, Ungureanu Ştefania, Dăescu Ecaterina, Gavriliță Mircea-Nicu, Ţîncu Cristian-Cosmin, Enache Alexandra

机构信息

Doctoral School, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

Institute of Forensic Medicine Timisoara, 300041 Timisoara, Romania.

出版信息

Diagnostics (Basel). 2024 Dec 5;14(23):2737. doi: 10.3390/diagnostics14232737.

DOI:10.3390/diagnostics14232737
PMID:39682644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11640619/
Abstract

BACKGROUND

Patients with traumatic injuries often represent the best hosts for healthcare-associated infections, especially pneumonia or bronchopneumonia. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic raised serious problems in the diagnosis and treatment of patients that had a SARS-CoV-2 infection and associated nosocomial bacterial bronchopneumonia. In forensic medicine, these aspects need to be considered when establishing the cause of death and the distinction between the two types of bronchopneumonia is of particular importance.

METHODS

We present nine cases that were autopsied at the Institute of Forensic Medicine Timisoara between 1 June 2020 and 31 December 2021, that presented traumatic injuries, a SARS-CoV-2 infection, and bronchopneumonia.

RESULTS

We focused on the main findings of the macroscopic and microscopic aspects of lung tissues.

CONCLUSIONS

We consider that the aspects we highlighted in this study, can be very useful in forensic practice in cases with a pluri-factorial pathology.

摘要

背景

创伤患者往往是医疗相关感染的最佳宿主,尤其是肺炎或支气管肺炎。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)大流行给感染SARS-CoV-2并伴有医院获得性细菌性支气管肺炎的患者的诊断和治疗带来了严重问题。在法医学中,在确定死因时需要考虑这些方面,区分这两种类型的支气管肺炎尤为重要。

方法

我们呈现了2020年6月1日至2021年12月31日期间在蒂米什瓦拉法医学研究所进行尸检的9例病例,这些病例存在创伤、SARS-CoV-2感染和支气管肺炎。

结果

我们重点关注了肺组织宏观和微观方面的主要发现。

结论

我们认为本研究中突出的这些方面在多因素病理学病例的法医实践中可能非常有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a997/11640619/ee457da2428e/diagnostics-14-02737-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a997/11640619/ee457da2428e/diagnostics-14-02737-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a997/11640619/ee457da2428e/diagnostics-14-02737-g002.jpg

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Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review.医院获得性肺炎需更新的十个问题:专家综述
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A meta-meta-analysis of co-infection, secondary infections, and antimicrobial resistance in COVID-19 patients.一项关于 COVID-19 患者合并感染、继发感染和抗菌药物耐药的荟萃荟萃分析。
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Diagnostics (Basel). 2023 May 26;13(11):1856. doi: 10.3390/diagnostics13111856.
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Effect of COVID-19 pneumonia infection control protocols on nosocomial infection incidence in trauma patients.新冠病毒肺炎感染防控方案对创伤患者医院感染发生率的影响。
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