Department of Microbiology, Fars Science and Research Branch, Islamic Azad University, Eqlid, Fars, Iran.
Department of Microbiology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Curr Microbiol. 2023 May 24;80(7):223. doi: 10.1007/s00284-023-03315-y.
The novel human coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which results in the coronavirus disease 2019 (COVID-19), has caused a serious threat to global public health. Therefore, many studies are performed on the causes and prevalence of this disease and the possible co-occurrence of the infection with other viral and bacterial pathogens is investigated. Respiratory infections predispose patients to co-infections and these lead to increased disease severity and mortality. Numerous types of antibiotics have been employed for the prevention and treatment of bacterial co-infection and secondary bacterial infections in patients with a SARS-CoV-2 infection. Although antibiotics do not directly affect SARS-CoV-2, viral respiratory infections often result in bacterial pneumonia. It is possible that some patients die from bacterial co-infection rather than virus itself. Therefore, bacterial co-infection and secondary bacterial infection are considered critical risk factors for the severity and mortality rates of COVID-19. In this review, we will summarize the bacterial co-infection and secondary bacterial infection in some featured respiratory viral infections, especially COVID-19.
新型人类冠状病毒，即严重急性呼吸综合征冠状病毒 2（SARS-CoV-2），可引起 2019 冠状病毒病（COVID-19），对全球公共卫生造成严重威胁。因此，许多研究致力于探讨这种疾病的病因和流行情况，以及感染该病毒与其他病毒和细菌病原体的可能共现。呼吸道感染使患者容易发生合并感染，这会导致疾病严重程度和死亡率增加。为预防和治疗 SARS-CoV-2 感染患者的细菌合并感染和继发细菌感染，已经使用了多种类型的抗生素。尽管抗生素不会直接影响 SARS-CoV-2，但病毒性呼吸道感染通常会导致细菌性肺炎。有些患者可能因细菌合并感染而非病毒本身而死亡。因此，细菌合并感染和继发细菌感染被认为是 COVID-19 严重程度和死亡率的关键危险因素。在这篇综述中，我们将总结一些特征性呼吸道病毒感染（尤其是 COVID-19）中的细菌合并感染和继发细菌感染。
