de Moura Edmilson Leal Bastos, Pereira Rinaldo Wellerson
Health Sciences Doctoral Program, University of Brasília (UnB), Brasilia 70910-900, Distrito Federal, Brazil.
School of Health Sciences, Distrito Federal University (UnDF), Brasilia 70710-907, Distrito Federal, Brazil.
J Clin Med. 2024 Nov 21;13(23):7038. doi: 10.3390/jcm13237038.
Sepsis is a pervasive condition that affects individuals of all ages, with significant social and economic consequences. The early diagnosis of sepsis is fundamental for establishing appropriate treatment and is based on warning scores and clinical characteristics, with positive microbiological cultures being the gold standard. Research has yet to identify a single biomarker to meet this diagnostic demand. Presepsin is a molecule that has the potential as a biomarker for diagnosing sepsis. In this paper, we present a narrative review of the diagnostic and prognostic performance of presepsin in different age groups. Given its particularities, it is identified that presepsin is a potential biomarker for sepsis at all stages of life.
脓毒症是一种普遍存在的病症，影响着所有年龄段的人群，会带来重大的社会和经济后果。脓毒症的早期诊断对于确定适当的治疗至关重要，其诊断基于预警评分和临床特征，微生物培养结果呈阳性是金标准。目前尚未找到一种单一的生物标志物来满足这一诊断需求。前降钙素是一种有潜力作为脓毒症诊断生物标志物的分子。在本文中，我们对前降钙素在不同年龄组中的诊断和预后性能进行了叙述性综述。鉴于其特殊性，前降钙素被确定为生命各阶段脓毒症的潜在生物标志物。
