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护理人员在院外分娩中使用催产素的情况:波兰人群六年回顾性分析

Situations in Which Oxytocin Was Administrated by Paramedics in Out-of-Hospital Births: A Retrospective Analysis over Six Years in the Polish Population.

作者信息

Wiciak Hanna, Strózik Mateusz, Smereka Adam, Fuchs Tomasz, Smereka Jacek

机构信息

Clinical Department of Gynecologic Surgery and Oncology, University Center of Obstetrics and Gynecology, Wroclaw Medical University, 50-367 Wroclaw, Poland.

Clinical Department of Obstetrics and Gynecology, University Center of Obstetrics and Gynecology, Wroclaw Medical University, 50-367 Wroclaw, Poland.

出版信息

J Clin Med. 2024 Nov 26;13(23):7175. doi: 10.3390/jcm13237175.

DOI:10.3390/jcm13237175
PMID:39685634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11642692/
Abstract

Postpartum haemorrhage (PPH) is a leading cause of maternal mortality worldwide, particularly in low- and middle-income countries, complicating 1% to 10% of deliveries. Despite improvement in prevention and management, variations in PPH definitions and measurement methods contribute to challenges in accurately assessing its incidence, with up to 90% of PPH-related deaths in high-income countries deemed avoidable through timely intervention. Oxytocin is the primary drug administered during labour or miscarriage, causing an increase in uterine muscle tone, which reduces bleeding and the risk of complications. The aim of the study was to assess the rate of oxytocin use by paramedics for out-of-hospital births in Poland and to verify adherence to WHO-recommended protocols for preventing postpartum haemorrhage in emergency prehospital settings. : We conducted a cross-sectional study using data from the Polish Central System for Emergency Medical Services Missions Monitoring covering all EMS interventions nationwide from 2018 to 2023. The study included cases where oxytocin was administered during EMS interventions for pregnant women, identified through ICD-10 codes (O30-O92), with 62 verified cases meeting the inclusion criteria. : Over 6 years, oxytocin was administered in 62 cases when paramedics responded to emergencies involving pregnant women. The mean age of the patients to whom the oxytocin was administered was 29.48 years (SD = 6.25) and ranged from 15 to 43 years. : Oxytocin is rarely administered by EMS teams at the prehospital stage. Oxytocin should be considered for incorporation into the set of medications that EMS teams can administer in prehospital settings. There is a need to train EMS teams in the management of pregnancy-related emergencies in accordance with the current medical guidelines.

摘要

产后出血(PPH)是全球孕产妇死亡的主要原因,在低收入和中等收入国家尤为突出,1%至10%的分娩会出现并发症。尽管在预防和管理方面有所改善,但PPH定义和测量方法的差异导致准确评估其发病率面临挑战,在高收入国家,高达90%的PPH相关死亡被认为可通过及时干预避免。催产素是分娩或流产期间使用的主要药物,可增加子宫肌张力,减少出血和并发症风险。本研究的目的是评估波兰护理人员在院外分娩时使用催产素的比例,并核实是否遵守世界卫生组织推荐的紧急院前环境中预防产后出血的方案。:我们进行了一项横断面研究,使用来自波兰中央紧急医疗服务任务监测系统的数据,涵盖2018年至2023年全国所有紧急医疗服务干预措施。该研究包括通过ICD-10编码(O30-O92)确定的在紧急医疗服务干预期间为孕妇使用催产素的病例,有62例经核实符合纳入标准。:在6年时间里,护理人员在应对涉及孕妇的紧急情况时,有62例使用了催产素。使用催产素的患者平均年龄为29.48岁(标准差=6.25),年龄范围为15至43岁。:紧急医疗服务团队在院前阶段很少使用催产素。应考虑将催产素纳入紧急医疗服务团队可在院前环境中使用的药物组合。有必要根据现行医学指南对紧急医疗服务团队进行与妊娠相关紧急情况管理方面的培训。

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本文引用的文献

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Emergency medical team interventions in Poland during out-of-hospital deliveries: A retrospective analysis.波兰院外分娩期间紧急医疗团队的干预措施:一项回顾性分析。
Adv Clin Exp Med. 2024 Mar 20. doi: 10.17219/acem/184141.
2
Therapeutic uses of oxytocin in stress-related neuropsychiatric disorders.催产素在应激相关神经精神疾病中的治疗用途。
Cell Biosci. 2023 Nov 28;13(1):216. doi: 10.1186/s13578-023-01173-6.
3
Epidemiology of Emergency Medical Services-Attended out-of-Hospital Deliveries and Complications in the United States.
美国急诊医疗服务机构参与的院外分娩及并发症的流行病学
Prehosp Emerg Care. 2024;28(7):890-897. doi: 10.1080/10903127.2023.2283892. Epub 2023 Nov 29.
4
Postpartum Hemorrhage: A Comprehensive Review of Guidelines.产后出血:指南综合综述
Obstet Gynecol Surv. 2022 Nov;77(11):665-682. doi: 10.1097/OGX.0000000000001061.
5
Comparison of European recommendations about patient blood management in postpartum haemorrhage.比较欧洲关于产后出血患者血液管理的建议。
Transfus Med. 2023 Apr;33(2):103-112. doi: 10.1111/tme.12927. Epub 2022 Nov 4.
6
Haemostatic support in postpartum haemorrhage: A review of the literature and expert opinion.产后出血的止血支持:文献回顾和专家意见。
Eur J Anaesthesiol. 2023 Jan 1;40(1):29-38. doi: 10.1097/EJA.0000000000001744. Epub 2022 Sep 22.
7
Preventing postpartum hemorrhage after cesarean delivery: a network meta-analysis of available pharmacologic agents.剖宫产术后预防产后出血:现有药物的网状Meta分析
Am J Obstet Gynecol. 2022 Mar;226(3):347-365. doi: 10.1016/j.ajog.2021.08.060. Epub 2021 Sep 14.
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The pediatric psychopharmacology of autism spectrum disorder: A systematic review - Part I: The past and the present.自闭症谱系障碍的儿科精神药理学:系统评价 - 第一部分:过去和现在。
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Aug 30;110:110326. doi: 10.1016/j.pnpbp.2021.110326. Epub 2021 Apr 20.
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Oxytocin in Schizophrenia: Pathophysiology and Implications for Future Treatment.精神分裂症中的催产素:病理生理学及对未来治疗的启示。
Int J Mol Sci. 2021 Feb 21;22(4):2146. doi: 10.3390/ijms22042146.
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Hematology Am Soc Hematol Educ Program. 2020 Dec 4;2020(1):542-546. doi: 10.1182/hematology.2020000139.