Son Woo Chul, Kim Sang Ah, Kim Ah Hyun, Cheon Hawyeong, Jeon Jae Yong
Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Biomedical Engineering Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea.
J Clin Med. 2024 Nov 27;13(23):7200. doi: 10.3390/jcm13237200.
: Breast cancer-related lymphedema (BCRL) reduces the quality of life of patients and limits their activities of daily living. Even though resistance exercises seemed to be safe in BCRL patients, it was still controversial that resistance exercises improve lymphedema. Therefore, we sought to evaluate the effects of forearm-targeted resistance exercises on BCRL using segmental bioelectrical impedance analysis (BIA). : This study was a pilot-controlled randomized trial, with patients divided into the intervention and the control group. Both groups received 30 min of complete decongestive therapy (CDT) for 2 weeks. In addition, the intervention group received forearm strengthening training including warm-up and cool-down for an extra 20 min, and the control group received stretching exercises. 5 kHz impedance ratios were assessed by segmental BIA before and after treatments. : Among the eighteen patients enrolled, ten were assigned to the intervention group, and eight were in the control group. Only the 5 kHz impedance ratio in the forearm segment of the intervention group showed a statistically significant difference. The effect sizes of the groups were 0.71 for the intervention group and 0.93 in the between-group comparison. : Forearm resistance exercises in patients with BCRL showed a significant decrease in extracellular fluid in the proximal forearm segment when using segmental BIA. Therefore, we suggest that resistance exercises targeting the forearm might be effective in treating lymphedema.
乳腺癌相关淋巴水肿(BCRL)会降低患者的生活质量并限制其日常生活活动。尽管抗阻运动在BCRL患者中似乎是安全的,但抗阻运动是否能改善淋巴水肿仍存在争议。因此,我们试图使用分段生物电阻抗分析(BIA)来评估针对前臂的抗阻运动对BCRL的影响。
本研究是一项试点对照随机试验,将患者分为干预组和对照组。两组均接受为期2周、每次30分钟的完全减压疗法(CDT)。此外,干预组额外接受20分钟包括热身和放松的前臂强化训练,对照组接受伸展运动。治疗前后通过分段BIA评估5kHz阻抗比。
在纳入的18名患者中,10名被分配到干预组,8名在对照组。仅干预组前臂段的5kHz阻抗比显示出统计学上的显著差异。干预组的效应量为0.71,组间比较为0.93。
使用分段BIA时,BCRL患者的前臂抗阻运动显示近端前臂段细胞外液显著减少。因此,我们建议针对前臂的抗阻运动可能对治疗淋巴水肿有效。