Zhang Zirui, Guo Luyan, Zhou Lizhi, Hao Xijun, Fan Yijing, Li Hong, Xu Huiqian, Hu Jiwei, Du Aijun, Wang Yaqi
North China University of Science and Technology, Tangshan, 063210, China.
Tangshan People's Hospital, Tangshan, 063000, China.
Support Care Cancer. 2025 Feb 14;33(3):194. doi: 10.1007/s00520-025-09256-5.
Explore the preventive effects of varying intensity progressive resistance exercise on breast cancer-related lymphedema.
A total of 114 breast cancer patients who underwent axillary lymph node dissection at Tangshan People's Hospital from January to April 2024 were included. Participants were randomly assigned to three groups: the control group received conventional care; intervention group 1 received conventional care + low-intensity progressive resistance exercise; and intervention group 2 received routine nursing + moderate and high-intensity progressive resistance exercise. Body composition and grip strength were assessed pre-intervention, post-intervention, and at 3 and 6 months follow-up to compare differences among the groups.
(1) Body composition: At post-intervention, 3 and 6 months follow-up, segmental water differences and extracellular water ratios, along with 1- and 5-kHz SFBIA in both intervention groups, were lower than in the control group. Intervention group 2 had a lower extracellular water ratio than group 1 at post-intervention, and at 3 months follow-up, group 2 showed lower water differences and extracellular water ratios than group 1, with slight variations at 6 months (P < 0.001). (2) Grip strength: At post-intervention, 3 months and 6 months follow-up, grip strength in intervention group 1 and intervention group 2 was higher than that in control group, and the difference was statistically significant (P < 0.001).
Resistance exercise enhances muscle strength and prevents lymphedema, with moderate-high-intensity exercise proving more effective than low intensity. Adverse events were minimal, suggesting that increasing resistance exercise intensity, while considering participants' conditions, may yield better preventive outcomes.
探讨不同强度渐进性抗阻运动对乳腺癌相关淋巴水肿的预防作用。
纳入2024年1月至4月在唐山市人民医院接受腋窝淋巴结清扫术的114例乳腺癌患者。参与者被随机分为三组：对照组接受常规护理；干预组1接受常规护理+低强度渐进性抗阻运动；干预组2接受常规护理+中高强度渐进性抗阻运动。在干预前、干预后以及随访3个月和6个月时评估身体成分和握力，以比较各组之间的差异。
（1）身体成分：在干预后、随访3个月和6个月时，两个干预组的节段性水分差异和细胞外水比例，以及1kHz和5kHz的生物电阻抗分析结果均低于对照组。干预后，干预组2的细胞外水比例低于干预组1；随访3个月时，干预组2的水分差异和细胞外水比例低于干预组1，6个月时差异略有变化（P<0.001）。（2）握力：在干预后、随访3个月和6个月时，干预组1和干预组2的握力均高于对照组，差异有统计学意义（P<0.001）。
抗阻运动可增强肌肉力量并预防淋巴水肿，中高强度运动比低强度运动更有效。不良事件极少，这表明在考虑参与者身体状况的同时增加抗阻运动强度可能会产生更好的预防效果。
