Yang Michelle Shigi, Abdallah Mohamed Bilal, Bashir Zubair, Khalife Wissam
Department of Cardiology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Department of Health and Human Performance, University of Houston, Houston, TX 77004, USA.
J Clin Med. 2024 Nov 29;13(23):7278. doi: 10.3390/jcm13237278.
Heart failure (HF) is a complex syndrome that significantly affects patients' physical, psychological, and socioeconomic well-being. Despite advances in guideline-directed medical therapy (GDMT), such as ACE inhibitors, beta-blockers, and SGLT2 inhibitors, HF continues to have a high global burden, with over 64 million affected worldwide and a five-year mortality rate of 50%. HF disrupts various life aspects, especially for younger patients (aged 35-55), who often face career interruptions due to severe symptoms like fatigue and frequent hospitalizations. These patients may struggle to maintain employment, resulting in financial instability compounded by high healthcare costs. Moreover, reduced exercise capacity and sexual dysfunction negatively impact patients' quality of life. The psychological toll of HF is profound, with many patients experiencing depression, anxiety, and stress. However, a positive mindset has been shown to improve survival rates, underscoring the need for holistic management approaches. Interventions like cognitive behavioral therapy (CBT) and remote monitoring technologies such as CardioMEMS offer promising avenues to improve quality of life and reduce hospitalizations. This review highlights the importance of a multidisciplinary, patient-centered approach to HF management. Tailoring care to align with individual goals, integrating psychosocial support, and enhancing patient education are vital in addressing both the clinical and personal challenges of HF. By adopting a comprehensive approach, healthcare providers can significantly improve long-term outcomes and quality of life for HF patients.
心力衰竭（HF）是一种复杂的综合征，严重影响患者的身体、心理和社会经济福祉。尽管在指南指导的药物治疗（GDMT）方面取得了进展，如使用血管紧张素转换酶抑制剂、β受体阻滞剂和钠-葡萄糖协同转运蛋白2抑制剂，但HF在全球范围内仍然负担沉重，全球有超过6400万人受到影响，五年死亡率为50%。HF扰乱了生活的各个方面，尤其是对于年轻患者（35 - 55岁），他们常常因疲劳和频繁住院等严重症状而面临职业中断。这些患者可能难以维持工作，导致经济不稳定，而高昂的医疗费用更是雪上加霜。此外，运动能力下降和性功能障碍对患者的生活质量产生负面影响。HF造成的心理负担也很沉重，许多患者会出现抑郁、焦虑和压力。然而，积极的心态已被证明可以提高生存率，这凸显了采取整体管理方法的必要性。认知行为疗法（CBT）等干预措施以及CardioMEMS等远程监测技术为改善生活质量和减少住院提供了有希望的途径。本综述强调了采用多学科、以患者为中心的方法来管理HF的重要性。根据个体目标调整护理、整合心理社会支持并加强患者教育对于应对HF的临床和个人挑战至关重要。通过采取全面的方法，医疗保健提供者可以显著改善HF患者的长期预后和生活质量。
