Kang Dong-Ho, Park Jae Hyeon, Yoon Chan, Choi Chi-Hyun, Lee Sanghee, Park Tae Hyun, Chang Sam Yeol, Jang Seong-Ho
Department of Orthopedic Surgery, Samsung Medical Center, Seoul 06351, Republic of Korea.
Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
J Clin Med. 2024 Dec 4;13(23):7377. doi: 10.3390/jcm13237377.
Chronic lower back pain (CLBP) is a global health issue leading to significant disability and socioeconomic burden. Traditional treatments, including exercise and cognitive behavioral therapy (CBT), are often limited by physical and temporal constraints. This study aimed to evaluate the efficacy of multidisciplinary digital therapeutics (MORA Cure LBP) compared to conventional treatments. This multicenter, randomized, controlled pilot study enrolled 46 participants. Participants were randomly assigned in a 1:1 ratio to either a MORA Cure LBP group or control group, which received conventional treatment. At eight weeks, both groups demonstrated improvements compared to baseline. No statistically significant differences were observed between the MORA Cure LBP and control groups in reductions in usual pain intensity (MORA Cure LBP: 3.1 ± 1.9 vs. control: 3.0 ± 1.5, = 0.809), worst pain intensity (MORA Cure LBP: 5.00 ± 2.18 vs. control: 4.27 ± 1.83, = 0.247), and functional disability (ODI, MORA Cure LBP: 15.6 ± 9.6 vs. control: 15.6 ± 10.0, > 0.999). Compliance was significantly higher in the MORA Cure LBP group during the first 4 weeks (MORA Cure LBP: 74.7% ± 27.4 vs. control: 53.1% ± 28.6, < 0.001). Both multidisciplinary digital therapeutics (MORA Cure LBP) and conventional treatments were effective in reducing pain and functional disability in patients with CLBP, with no significant differences between the two groups. Digital therapeutics, particularly those that integrate CBT and exercise, offer promising alternatives to conventional therapies by improving accessibility and potentially enhancing patient engagement.
慢性下腰痛（CLBP）是一个全球性的健康问题，会导致严重的残疾和社会经济负担。包括运动和认知行为疗法（CBT）在内的传统治疗方法，常常受到身体和时间限制。本研究旨在评估多学科数字疗法（MORA Cure LBP）与传统治疗方法相比的疗效。这项多中心、随机、对照的试点研究招募了46名参与者。参与者按1:1的比例随机分配到MORA Cure LBP组或接受传统治疗的对照组。在八周时，与基线相比，两组均有改善。在通常疼痛强度的降低方面（MORA Cure LBP组：3.1±1.9，对照组：3.0±1.5，P = 0.809）、最严重疼痛强度方面（MORA Cure LBP组：5.00±2.18，对照组：4.27±1.83，P = 0.247）以及功能障碍方面（ODI，MORA Cure LBP组：15.6±9.6，对照组：15.6±10.0，P>0.999），MORA Cure LBP组和对照组之间未观察到统计学上的显著差异。在最初4周内，MORA Cure LBP组的依从性显著更高（MORA Cure LBP组：74.7%±27.4，对照组：53.1%±28.6，P<0.001）。多学科数字疗法（MORA Cure LBP）和传统治疗方法在减轻CLBP患者的疼痛和功能障碍方面均有效，两组之间无显著差异。数字疗法，特别是那些整合了CBT和运动的疗法，通过提高可及性并可能增强患者参与度，为传统疗法提供了有前景的替代方案。
